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Multiplexed nanoplasmonic biosensor for one-step simultaneous detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine

Related publications (36)

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The use of microfluidic droplets has become a powerful tool for the screening and manipulation of cells. However, currently this is restricted to assays involving a single cell type. Studies on the interaction of different cells (e.g. in immunology) as wel ...

2015

A microfluidic platform for high-throughput multiplexed protein quantitation

Sebastian Maerkl, Jose Luis Garcia Cordero, Francesca Volpetti

We present a high-throughput microfluidic platform capable of quantitating up to 384 biomarkers in 4 distinct samples by immunoassay. The microfluidic device contains 384 unit cells, which can be individually programmed with pairs of capture and detection ...

Public Library of Science2015

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We describe a multiplexing technology, named Evalution, based on novel digitally encoded microparticles in microfluidic channels. Quantitative multiplexing is becoming increasingly important for research and routine clinical diagnostics, but fast, easy-to- ...

Amer Chemical Soc2015

A novel cmos image sensor with event/change detection and reduced data redundancy

Giovanni De Micheli, Sandro Carrara, Gözen Köklü

A Digital Pixel Sensor (DPS) based CMOS camera configured to record frames and comprising an event detection sensor configured to look for an event happening in a determined frame, comprising an array of event detection pixels, a first reference voltage ge ...

2014

Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Paolo Silacci, Julien Michel Ghaye, Chiara Succa, Guy Vergères

State-of-the-art techniques for measuring and monitoring gene level expression rely on messenger RNA (mRNA) extraction and quantification, usually based on the concept of reverse transcription polymerase chain reaction. In this paper, we take adva ...

Ieee2014

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We propose a novel approach to the real-time landing site detection and assessment in unconstrained man-made environments using passive sensors. Because this task must be performed in a few seconds or less, existing methods are often limited to simple loca ...

Springer Verlag2014

Extremely sensitive protein detection is crucial for early diagnosis and monitoring of diseases. Present day’s limit of detection for an antibody-antigen recognition-based immunoassay in serum without having to use special target antigen amplification tech ...

EPFL2012

Functional single-cell hybridoma screening using droplet-based microfluidics

Christoph Merten

Monoclonal antibodies can specifically bind or even inhibit drug targets and have hence become the fastest growing class of human therapeutics. Although they can be screened for binding affinities at very high throughput using systems such as phage display ...

2012

Micro segmented-flow in biochemical and cell-based assays

Christoph Merten

Micro-segmented flow (e.g. in microfluidic channels, capillaries or a length of tubing) has become a promising technique in modern biology. Compared to conventional formats such as microtiter plates, sample volumes can be reduced about 1000-fold, thus allo ...

2012

A microfluidic-based frequency-multiplexing impedance sensor (FMIS)

Philippe Renaud, Arnaud Bertsch, Robert Meissner, Pierre Joris, Bilge Eker

We present a novel technology for the simultaneous and simple impedimetric screening of multiple microfluidic channels with only one electrode pair. We have exploited the frequency dimension to distinguish between up to three channels. Each ‘sub-sensor’ po ...

2012