Publications related to Heterobimetallic Ru(mu-dppm)Fe and homobimetallic Ru(mu-dppm)Ru complexes as potential anti-cancer agents

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song, Steve Comby

The homoditopic ligand

H_2L^{C3}

has been designed to form neutral triple-stranded bimetallic helicates of overall composition [

Ln_2(L^{C3})_3

]. The grafting of the polyoxyethylene fragments ensures water solubility and also favors cell penetration whi ...

2007

Gel-free IEF in a membrane-sealed multicompartment cell for proteome prefractionation

Hubert Girault, Hoang-Trang Lam

A minidevice for performing gel-free proteome prefractionation via conventional IEF in soluble carrier ampholyte buffers is reported here. It consists of a compact block of poly-oxymethylene in which eight samples and two electrode chambers are machined. E ...

2007

Pyrrolidine derivatives as new inhibitors of alpha-mannosidases and growth inhibitors of human cancer cells

Pierre Vogel, Sandrine Gerber, Hélène Fiaux

New pyrrolidine-3,4-diol derivatives were prepared from D-(-)- and L(+)-phenylglycinol and tested for their ability to inhibit 25 commercial glycosidases. The influence of the substitution of the lateral side chain and of the pyrrolidine ring on the enzyme ...

2006

Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes

Paul Joseph Dyson, Andrew Douglas Phillips, Claudine Scolaro, Gianni Sava

Ten complexes of general formula [Ru(η6-arene)Cl2(L)], [Ru(η6-arene)Cl(L)2][X], and [Ru(η6-arene)(L)3][X]2 (η6-arene = benzene, p-cymene; L = imidazole, ...

2006

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

Paul Joseph Dyson, Gabor Laurenczy, Claudine Scolaro, Gianni Sava

The antitumor activity of the organometallic ruthenium(II)-arene complexes, RuCl2(eta(6)-arene)(PTA), (arene = p-cymene, toluene, benzene, benzo-15-crown-5, 1-ethylbenzene-2,3-dimethylimidazolium tetrafluoroborate, ethyl benzoate, hexamethylbenzene; PTA = ...

2005

Non-iterative asymmetric synthesis of C-15 polyketide spiroketals

Pierre Vogel, Kai Torsten Meilert

The 2,2'-methylenebis[furan] (1) was converted to 1-{(4R,6S))-6-[(2R)-2,4-dihydroxybutyl]-2,2-dimethyl-1,3-dioxan-4-yl}-3- [(2R,4R)-tetrahydro-4,6-dihydroxy-2H-pyran-2-yl)propan-2-one ((+)-18) and its (4S)-epimer (-)-19 with high stereo- and enantioselecti ...

2004

Notch1 can contribute to viral-induced transformation of primary human keratinocytes

Peter Martin Beard

The human papillomavirus (HPV) is the most significant causative agent in the development of cervical cancer. Despite its presence in almost all cervical cancers, HPV by itself is unable to transform a normal cell to a cancerous one. Instead, additional ce ...

2003

Synthesis of cyclo-β-tripeptides and their biological in vitro evaluation as antiproliferatives against the growth of human cancer cell lines

Karl Gademann

A number of cyclo-β-tripeptides and their linear precursors were subjected to primary biol. evaluation for cancer-cell growth inhibition (one-dose, three-cell essay), and the five most active ones were then tested in the anti-tumor screen of the National C ...

2001

High-resolution holography and biopsy: Preliminary results

Christian Depeursinge

For holographic biopsy purposes, holograms of biological tissue samples have been recorded in vitro to establish the possibility of differentiating tissues on the holograms. With the use of specific absorbing dyes for staining tissues, the contrast has bee ...

1995

Heterobimetallic Ru(mu-dppm)Fe and homobimetallic Ru(mu-dppm)Ru complexes as potential anti-cancer agents

Graph Chatbot

Chat with Graph Search

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

Gel-free IEF in a membrane-sealed multicompartment cell for proteome prefractionation

Pyrrolidine derivatives as new inhibitors of alpha-mannosidases and growth inhibitors of human cancer cells

Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

Non-iterative asymmetric synthesis of C-15 polyketide spiroketals

Notch1 can contribute to viral-induced transformation of primary human keratinocytes

Synthesis of cyclo-β-tripeptides and their biological in vitro evaluation as antiproliferatives against the growth of human cancer cell lines

High-resolution holography and biopsy: Preliminary results

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

Notch1 can contribute to viral-induced transformation of primary human keratinocytes

Synthesis of cyclo-β-tripeptides and their biological in vitro evaluation as antiproliferatives against the growth of human cancer cell lines

Synthesis, Characterization, and in Vitro Evaluation of Novel Ruthenium(II) η6-Arene Imidazole Complexes

Pyrrolidine derivatives as new inhibitors of alpha-mannosidases and growth inhibitors of human cancer cells

Gel-free IEF in a membrane-sealed multicompartment cell for proteome prefractionation

Non-iterative asymmetric synthesis of C-15 polyketide spiroketals

A Polyoxyethylene-Substituted Bimetallic Europium Helicate for Luminescent Staining of Living Cells

High-resolution holography and biopsy: Preliminary results