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The standard model (SM) production of four top quarks () in proton-proton collision is studied by the CMS Collaboration. The data sample, collected during the 2016-2018 data taking of the LHC, corresponds to an integrated luminosity of 137 fb at a center-of-mass energy of 13 TeV. The events are required to contain two same-sign charged leptons (electrons or muons) or at least three leptons, and jets. The observed and expected significances for the signal are respectively 2.6 and 2.7 standard deviations, and the cross section is measured to be 12.6 fb. The results are used to constrain the Yukawa coupling of the top quark to the Higgs boson, , yielding a limit of $|{y_{\mathrm{t}}/y_{\mathrm{t}}^{\mathrm{SM}}}|
Jian Wang, Matthias Finger, Qian Wang, Yiming Li, Matthias Wolf, Varun Sharma, Yi Zhang, Konstantin Androsov, Jan Steggemann, Leonardo Cristella, Xin Chen, Davide Di Croce, Arvind Shah, Rakesh Chawla, Chao Wang, João Miguel das Neves Duarte, Tagir Aushev, Tian Cheng, Yixing Chen, Werner Lustermann, Andromachi Tsirou, Alexis Kalogeropoulos, Andrea Rizzi, Ioannis Papadopoulos, Paolo Ronchese, Hua Zhang, Siyuan Wang, Jessica Prisciandaro, Peter Hansen, Tao Huang, David Vannerom, Michele Bianco, Sebastiana Gianì, Kun Shi, Wei Shi, Abhisek Datta, Wei Sun, Jian Zhao, Thomas Berger, Federica Legger, Doohyun Kim, Bertrand François, Bandeep Singh, Ji Hyun Kim, Donghyun Kim, Dipanwita Dutta, Zheng Wang, Sanjeev Kumar, Wei Li, Yong Yang, Geng Chen, Yi Wang, Ajay Kumar, Ashish Sharma, Georgios Anagnostou, Joao Varela, Csaba Hajdu, Muhammad Ahmad, Ekaterina Kuznetsova, Ioannis Evangelou, Matthias Weber, Muhammad Shoaib, Milos Dordevic, Vineet Kumar, Vladimir Petrov, Francesco Fiori, Quentin Python, Meng Xiao, Sourav Sen, Viktor Khristenko, Fan Xia, Xiao Wang, Kai Yi, Jing Li, Rajat Gupta, Zhen Liu, Muhammad Waqas, Hui Wang, Seungkyu Ha, Maren Tabea Meinhard, Giorgia Rauco, Ali Harb, Benjamin William Allen, Long Wang, Pratyush Das, Miao Hu, Anton Petrov, Xin Gao, Chen Chen, Valérie Scheurer, Giovanni Mocellin, Muhammad Ansar Iqbal, Lukas Layer
Jian Wang, Matthias Finger, Qian Wang, Yiming Li, Matthias Wolf, Varun Sharma, Yi Zhang, Konstantin Androsov, Jan Steggemann, Leonardo Cristella, Xin Chen, Davide Di Croce, Arvind Shah, Rakesh Chawla, Chao Wang, João Miguel das Neves Duarte, Tagir Aushev, Tian Cheng, Yixing Chen, Werner Lustermann, Andromachi Tsirou, Alexis Kalogeropoulos, Andrea Rizzi, Ioannis Papadopoulos, Paolo Ronchese, Hua Zhang, Siyuan Wang, Jessica Prisciandaro, Peter Hansen, Tao Huang, David Vannerom, Michele Bianco, Sebastiana Gianì, Kun Shi, Wei Shi, Abhisek Datta, Wei Sun, Jian Zhao, Thomas Berger, Federica Legger, Doohyun Kim, Bertrand François, Bandeep Singh, Ji Hyun Kim, Donghyun Kim, Dipanwita Dutta, Zheng Wang, Sanjeev Kumar, Wei Li, Yong Yang, Geng Chen, Yi Wang, Ajay Kumar, Ashish Sharma, Georgios Anagnostou, Joao Varela, Csaba Hajdu, Muhammad Ahmad, Ekaterina Kuznetsova, Ioannis Evangelou, Matthias Weber, Muhammad Shoaib, Milos Dordevic, Vineet Kumar, Vladimir Petrov, Francesco Fiori, Meng Xiao, Sourav Sen, Viktor Khristenko, Xiao Wang, Kai Yi, Jing Li, Rajat Gupta, Zhen Liu, Muhammad Waqas, Hui Wang, Seungkyu Ha, Maren Tabea Meinhard, Giorgia Rauco, Ali Harb, Long Wang, Pratyush Das, Miao Hu, Anton Petrov, Xin Gao, Chen Chen, Valérie Scheurer, Giovanni Mocellin, Muhammad Ansar Iqbal, Lukas Layer