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Obtaining high resolution 3D quantitative images is critical for elucidating the relationship between cell dynamics and physiological or pathological processes. However the feasibility of such cellular dynamic studies is limited by the resolution of the 3D ...
Time-resolved measurements of tissue autofluorescence (AF) excited at 405 nm were carried out with an optical-fiber-based spectrometer in the bronchi of 11 patients. The objectives consisted of assessing the lifetime as a new tumor/normal (T/N) tissue cont ...
It is now widely acknowledged, among communities of researchers and engineers of very different horizons, that speckle interferometry (SI) offers powerful techniques to characterize mechanical rough surfaces with a submicronic accuracy in static or quasi-s ...
The present thesis develops some specific aspects of digital holographic microscopy (DHM), namely the effect of shot noise on the phase image accuracy, the use of DHM in micro-tomography and in aberrations evaluation of a microscope objective (MO). DHM is ...
Fourier or spectral domain optical coherence tomography (FDOCT) is a multi-dimensional interferometric imaging modality that has attracted increasing interest during the last few years. The reason is its outstanding sensitivity allowing high speed 2D and 3 ...
Recently, we have experimentally demonstrated a new form of cross-sectional, coherence-gated fluorescence imaging referred to as SD-FCT (‘spectral-domain fluorescence coherence tomography’). Imaging in SD-FCT is accomplished by spectrally detecting self-in ...
Substantial improvements in the nanofabrication and characteristics of gold Fresnel zone plates yielded unprecedented resolution levels in hard-x-ray microscopy. Tests performed on a variety of specimens with 8-10 keV photons demonstrated a first-order lat ...
The most common optical distance imaging methods (triangulation, interferometry and time-of-flight ranging) can all be described in a unified way as linear shift-invariant systems in which the determination of distance corresponds to the measurement of a s ...
Autofluorescence (AF) bronchoscopy is a useful tool for early cancer detection. However, the mechanisms involved in this diagnosis procedure are poorly understood. We present a clinical autofluorescence imaging study to assess the depth of the principal co ...
The three-dimensional trap stiffness of optical tweezers formed with high-NA micromirrors is investigated by back-focal-plane interferometry and power spectrum analysis. Normalized stiffness values of kappa(xy)/P-trap =1.2(mu N/m)/mW and kappa(z)/P-trap = ...
