Coarse-grained modelingCoarse-grained modeling, coarse-grained models, aim at simulating the behaviour of complex systems using their coarse-grained (simplified) representation. Coarse-grained models are widely used for molecular modeling of biomolecules at various granularity levels. A wide range of coarse-grained models have been proposed. They are usually dedicated to computational modeling of specific molecules: proteins, nucleic acids, lipid membranes, carbohydrates or water.
Microscopic scaleThe microscopic scale () is the scale of objects and events smaller than those that can easily be seen by the naked eye, requiring a lens or microscope to see them clearly. In physics, the microscopic scale is sometimes regarded as the scale between the macroscopic scale and the quantum scale. Microscopic units and measurements are used to classify and describe very small objects. One common microscopic length scale unit is the micrometre (also called a micron) (symbol: μm), which is one millionth of a metre.
Ratio estimatorThe ratio estimator is a statistical estimator for the ratio of means of two random variables. Ratio estimates are biased and corrections must be made when they are used in experimental or survey work. The ratio estimates are asymmetrical and symmetrical tests such as the t test should not be used to generate confidence intervals. The bias is of the order O(1/n) (see big O notation) so as the sample size (n) increases, the bias will asymptotically approach 0. Therefore, the estimator is approximately unbiased for large sample sizes.
Natural exponential familyIn probability and statistics, a natural exponential family (NEF) is a class of probability distributions that is a special case of an exponential family (EF). The natural exponential families (NEF) are a subset of the exponential families. A NEF is an exponential family in which the natural parameter η and the natural statistic T(x) are both the identity. A distribution in an exponential family with parameter θ can be written with probability density function (PDF) where and are known functions.
EconometricsEconometrics is an application of statistical methods to economic data in order to give empirical content to economic relationships. More precisely, it is "the quantitative analysis of actual economic phenomena based on the concurrent development of theory and observation, related by appropriate methods of inference". An introductory economics textbook describes econometrics as allowing economists "to sift through mountains of data to extract simple relationships". Jan Tinbergen is one of the two founding fathers of econometrics.
Interacting particle systemIn probability theory, an interacting particle system (IPS) is a stochastic process on some configuration space given by a site space, a countably-infinite-order graph and a local state space, a compact metric space . More precisely IPS are continuous-time Markov jump processes describing the collective behavior of stochastically interacting components. IPS are the continuous-time analogue of stochastic cellular automata.
German tank problemIn the statistical theory of estimation, the German tank problem consists of estimating the maximum of a discrete uniform distribution from sampling without replacement. In simple terms, suppose there exists an unknown number of items which are sequentially numbered from 1 to N. A random sample of these items is taken and their sequence numbers observed; the problem is to estimate N from these observed numbers. The problem can be approached using either frequentist inference or Bayesian inference, leading to different results.
