Publication
Electronic readout of DNA amplification in nanoliter chambers. Strategies towards highly parallel semiconductor-based nucleic acid amplification testing.
Related publications (132)
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In this study, we compare the electrical and optical signal transduction of nanoscale biosensors based on single -walled carbon nanotubes (SWCNTs). Solution processable single-stranded (ss) DNA-wrapped SWCNTs were used for the fabrication of the distinct s ...
ELSEVIER ADVANCED TECHNOLOGY2022Electrochemical sensors for the detection of SARS-CoV-2 virus
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Coronavirus (COVID-19), a deadly pandemic has spread worldwide and created many global health issues. Though methods of its detection are being continuously developed for the early detection and monitoring of COVID-19, still there is need for more novel me ...
ELSEVIER SCIENCE SA2022An epidermal wearable microfluidic patch for simultaneous sampling, storage, and analysis of biofluids with counterion monitoring
Silvia Demuru, Brince Paul Kunnel
Simultaneous access to different biofluids enables an accurate analysis of multiple analytes, leading to a precision diagnosis and appropriate medication. Additionally, establishing a relationship between various markers in different biofluids and their co ...
ROYAL SOC CHEMISTRY2022Integration of Ultra-Low Volume Pneumatic Microfluidics with a Three-Dimensional Electrode Network for On-Chip Biochemical Sensing
Carlotta Guiducci, Saurabh Tomar, Thomas Ernst
This paper reports a novel miniaturized pseudo reference electrode (RE) design for biasing Ion Sensitive Field Effect Transistors (ISFETs). It eliminates the need for post-CMOS processing and can scale up in numbers with the CMOS scaling. The presented des ...
2021Controlling the immobilization process of an optically enhanced protein microarray for highly reproducible immunoassay
By virtue of its high throughput multiplex detection capability, superior read-out sensitivity, and tiny analyte consumption, an optically enhanced protein microarray assay has been developed as a promising diagnostic tool for various applications, ranging ...
ROYAL SOC CHEMISTRY2021An Ultra Low-Noise Micropower PPG Sensor
Nowadays, efficient and remote health monitoring is becoming increasingly important, given both the ageing of population and the combined action of an increase in obesity level and cardiovascular diseases. The healthcare industry is becoming more reliant o ...
EPFL2020Microfluidic systems for cancer diagnostics
Sebastian Maerkl, Jose Luis Garcia Cordero
Although not employed in the clinic as of yet, microfluidic systems are likely to become a key technology for cancer diagnostics and prognosis. Microfluidic devices have been developed for the analysis of various biomarkers including circulating tumor cell ...
CURRENT BIOLOGY LTD2020Reconfigurable microfluidics: real-time shaping of virtual channels through hydrodynamic forces
To break the current paradigm in microfluidics that directly links device design to functionality, we introduce microfluidic "virtual channels" that can be dynamically shaped in real-time. A virtual channel refers to a flow path within a microfluidic flow ...
2020Modular interface and experimental setup for in-vacuum operation of microfluidic devices
Luis Guillermo Villanueva Torrijo, Annalisa De Pastina, Damien Maillard, Tom Larsen
We report on the design and operation of a world-to-chip microfluidic interface and experimental setup for fluidic micro- and nano-electromechanical systems. The central component of the interface is an engineered polyether ether ketone connector that brin ...
AMER INST PHYSICS2019Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip
Bart Deplancke, Esther Amstad, Johannes Julius Bues, Riccardo Dainese, Marjan Biocanin
Single-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution. One of the catalyzing technologies is single cell droplet microfluidics, ...
ROYAL SOC CHEMISTRY2019