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We present a technology for the fabrication of three dimensional microfluidic channels in optically transparent substrates consisting of polymers with different properties. The microstructures are fabricated using polymer replication techniques with a view ...
Selective transport and sorting of particles in microfluidic devices by electroosmosis is complicated due to superposition of uncontrolled hydrodynamic pressure contributions on the electroosmotic force. In this paper, we present a microfluidic concept for ...
The study of intracellular communication requires devices that can not only monitor the bioelectric activity, but also control and observe the biochemical environment at the cellular level. This paper reports on the development and characterisation of impl ...
There has been a recent trend towards the miniaturization of analytical tools, but what are the advantages of microfluidic devices and when is their use appropriate? Recent advances in the field of micro-analytical systems can be classified according to in ...
Spark assisted chemical engraving (SACE) is a method for 3D microstructuring of glass or other non-conductive materials with high aspect ratio and smooth surface quality. It is applicable for rapid prototyping of microfluidic devices, for MEMS interfacing ...
Microfluidic devices are a promising new tool for studying and optimizing (bio)chemical reactions and analyses. Many (bio)chemical reactions require accurate temperature control, such as for example thermocycling for PCR. Here, a new integrated temperature ...
In analytical separation technology there is a great demand for faster and more effective separation process. Miniaturization is a suitable technique for satisfying this demand because the reduction of the separation systems in size would give increased se ...
This paper reviews recent developments in integrated fluidic mesosystems, based on low-temperature co-fired ceramic (LTCC) technology, in this laboratory and elsewhere. LTCC is shown to be an advantageous technique for integrated fluidic systems, due to it ...
In order to improve the throughput of the traditional “Two Electrode Voltage Clamp” (TEVC) measurements on Xenopus oocytes, we present here a chip-based non-invasive technique for the measurement of ion channels activity. We focus especially on the integra ...