Generative machine learning produces kinetic models that accurately characterize intracellular metabolic states
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
Living organisms can catalyze many thousands of biochemical reactions that they use to convert energy and matter, which provides them with the essentials for life. The sum of these chemical reactions happening in an organism is called metabo-lism. Understa ...
Lipids carry an important role in cell structure and function, as well as in the physiopathology of multiple diseases. Maintenance of the lipid profiles should be tightly regulated for preserving membrane permeability, cell integrity and several other func ...
Lipids carry a very important role in cell structure and function, as well as in the physiopathology of many diseases. Maintenance of the lipid profiles should be tightly regulated as it is very important for preserving membrane permeability, cell integrit ...
Metabolism is the sum of the chemical interactions occurring inside a cell that process nutrients into cellular constituents and energy. Research in the recent decades has enabled the characterization of metabolic reaction networks for multiple organisms. ...
Exploration methods combine parametric energy assessments and data visualization to support building designers at early design stages. When exploration methods come to Life-Cycle Assessment (LCA) and the Global Warming Potential (GWP) assessment, a larger ...
Flavonoids are natural plant-derived compounds which have immense applications in pharmaceutical industry and have attracted the attention of both the industry and researchers involved in all fields of biology and medicine. Microbial production systems can ...
As Saitta et al. report in [1], the flipped classroom model builds on several well-known teaching approaches. In particular, using in-class time for more active learning activities as been constantly shown by research to improve learning [2]. In this prese ...
Over the last decades, yeast has become a key model organism for the study of lipid biochemistry. Because the regulation of lipids has been closely linked to various physiopathologies, the study of these biomolecules could lead to new diagnostics and treat ...
Since flux balance analysis (FBA) has been introduced in Systems Biology, several attempts have been made at supplementing it with expression data [1-3]. With the notable exception of O’Brien et al. [1], none of them account directly for the enzyme product ...
Large-scale kinetic models are used for designing, predicting, and understanding the metabolic responses of living cells. Kinetic models are particularly attractive for the biosynthesis of target molecules in cells as they are typically better than other t ...
