Publications related to Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

Daniel Constam, Marine Marie Kraus, Anne Grapin-Botton

Bicaudal C homologue 1 (Bicc1) knockout in mice causes polycystic kidney disease and pancreas development defects, including a reduction in insulin-producing β-cells and ensuing diabetes. We therefore screened 137 patients with renal abnormalities or assoc ...

2011

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

László Forró, Aleksandra Radenovic, Andras Kis

Strong epidemiologic evidence suggests an association between Alzheimer disease (AD) and type 2 diabetes. To determine if amyloid beta (A

\beta

) and hyperphosphorylated tau occurs in type 2 diabetes, pancreas tissues from 21 autopsy cases (10 type 2 diabe ...

Elsevier2010

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

Johan Auwerx, Kristina Schoonjans, Thijs Pols

Incretin-based therapies have shown promise in the treatment of type 2 diabetes. Here we review our current understanding of TGR5 as a target to induce glucagon-like peptide-1 (GLP-1) secretion. These new observations suggest that TGR5 agonists may constit ...

Elsevier Masson2010

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Kamiar Aminian, Stéphane Armand

Gait characteristics and balance are altered in diabetic patients. Little is known about possible treatment strategies. This study evaluates the effect of a specific training programme on gait and balance of diabetic patients. ...

2010

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Theo Lasser, Michael Friedrich, Rainer Leitgeb, Anne Grapin-Botton, Martin Villiger, Joan Goulley

Aims/hypothesis Structural and functional imaging of the islets of Langerhans and the insulin-secreting beta cells represents a significant challenge and a long-lasting objective in diabetes research. In vivo microscopy offers a valuable insight into beta ...

Springer Verlag2009

Reduced cyclic stretch, endothelial dysfunction, and oxidative stress: an ex vivo model

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Paolo Silacci, Tyler Nerton Thacher, Veronica Gambillara

The objective of this study was to investigate whether reduction of cyclic circumferential stretch will impair endothelial function and elevate basal levels of oxidative stress, both known risk factors linked to cardiovascular disease. ...

2009

Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation

Jacques Fellay

Immunosuppressive and antiviral prophylactic drugs are needed to prevent acute rejection and infection after transplantation. We assessed the efficacy and safety of the introduction of universal valganciclovir prophylaxis in combination with a tacrolimus/m ...

Swiss Medical Publishers Ltd / EMH Swiss Medical Publishers2007

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

Johan Auwerx

CONTEXT: The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been ...

2006

Treatment of cytomegalovirus infection or disease in solid organ transplant recipients with valganciclovir

Jacques Fellay

Letter / Comment on: Am J Transplant. 2004 Nov;4 Suppl 10:51-8 and Am J Transplant. 2005 Feb;5(2):218-27 ...

Wiley-Blackwell2005

Organ Transplantation Management

Rachele Fuzzati

Organ transplantation is a widespread and effective technique to treat important diseases and can often make the difference between life and death of some patients. Given a donor, finding the best recipient for one of his organs means finding, in the short ...

2005

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

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Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Reduced cyclic stretch, endothelial dysfunction, and oxidative stress: an ex vivo model

Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

Treatment of cytomegalovirus infection or disease in solid organ transplant recipients with valganciclovir

Organ Transplantation Management

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

The gait and balance of patients with diabetes can be improved: a randomised controlled trial

Reduced cyclic stretch, endothelial dysfunction, and oxidative stress: an ex vivo model

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

Efficacy and safety of universal valganciclovir prophylaxis combined with a tacrolimus/mycophenolate-based regimen in kidney transplantation

Organ Transplantation Management

Treatment of cytomegalovirus infection or disease in solid organ transplant recipients with valganciclovir

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects