Pf3 coat protein forms voltage-gated ion channels in planar lipid bilayers
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The actor model has been a model of choice for building reliable distributed systems. On one hand, it ensures that message-processing is serialized within each actor, preserving the familiar sequential programming model. On the other hand, programs written ...
The fatty acid amide hydrolase (FAAH) regulates the endocannabinoid system cleaving primarily the lipid messenger anandamide. FAAH has been well characterized over the years and, importantly, it represents a promising drug target to treat several diseases, ...
Scaling down to nanometer size fluidic conduits has opened a new window into the world of sensing and manipulation of nanoscale species. Thousands of publications and hundreds of patents in this field are only a starting point for exploring and manipulatin ...
The scaling of device technologies poses new challenges, not only in circuit design, but also in device modeling, especially because of the short-channel effects and the emergence of novel phenomena like ballistic transport. Nonetheless, it enables the des ...
Salt sensitive (pea) and salt tolerant (barley) species were used to understand the physiological basis of differential salinity tolerance in crops. Pea plants were much more efficient in restoring otherwise depolarized membrane potential thereby effective ...
In transport experiments, the quantum nature of matter becomes directly evident when changes in conductance occur only in discrete steps1, with a size determined solely by Planck's constant h. Observations of quantized steps in electrical conductance2,3 ha ...
We demonstrate the fabrication of fully printed thin dielectric elastomer actuators (DEAs), reducing the operation voltage below 300V while keeping good actuation strain. DEAs are soft actuators capable of strains greater than 100% and response times below ...
In this paper, we present an analytical semiempirical model of the profile of the channel charge and potential in quasi-ballistic double-gate (DG) MOSFETs. The charge model is based on the premise of separating the charge density in the quasi-ballistic cha ...
Cyclic nucleotide-modulated ion channels are important for signal transduction and pacemaking in eukaryotes. The molecular determinants of ligand gating in these channels are still unknown, mainly because of a lack of direct structural information. Here we ...
Porins, like outer membrane protein G (OmpG) of Escherichia coli, are ideal templates among ion channels for protein and chemical engineering because of their robustness and simple architecture. OmpG shows fast transitions between open and closed states, w ...