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The Laboratory of Bionanophotonic Systems (BIOS) at EPFL specializes in developing ultra-sensitive spectroscopy and sensing technologies for real-time, label-free detection of biomolecules. They utilize nanophotonic technologies like nanoplasmonics and metamaterials, integrating on-chip sensors with micro nanofluidic systems. BIOS also explores nanophotonics for on-chip optical communications. Their research focuses on lab-on-a-chip devices, optical nano-biosensors, vibrational spectroscopy, plasmonics, micro and nanofluidics, and nanofabrication. BIOS has made significant contributions to the field, as evidenced by their publications on topics such as plasmonic infrared sensors, spatiotemporal monitoring of single-cell secretions, and label-free plasmonic microarrays for cell analysis.