Laboratory of Microcircuit Neuroscience

The Laboratory of Microcircuit Neuroscience (LNMC), led by Professor Henry Markram, focuses on understanding the structure, function, and plasticity of neural microcircuits in the neocortex. They investigate the computational capabilities of neocortical microcircuits, emphasizing their role as the fundamental unit of computation in the brain. LNMC systematically characterizes the electrophysiological, structural, and molecular properties of individual neurons, as well as the rules of connectivity and synaptic properties within microcircuits. Their research also delves into neuromodulation effects on microcircuit dynamics and explores the link between microcircuit alterations and autism. LNMC's work contributes to the Blue Brain Project by providing data for building realistic brain region models through detailed computer simulations.