Catégorie
Zoologie
Publications associées (1 000)
Reconstruction and analysis of genome-scale metabolic networks in single organisms and microbial communities
Microorganisms are a key component in the chain of life. They are essential for agriculture, produce a large proportion of oxygen, and play a central role in the cycle of elements. Microorganisms are widely used in the production of food and alcoholic beve ...
EPFL2024Assessing the universality of Habitat Suitability Indexes (HSI) for brown trout (Salmo trutta L.) In relation to ecohydraulic variables
Giovanni De Cesare, Paolo Perona, Giulio Calvani, Francesca Padoan
The Habitat Suitability Index (HSI) is a quantitative index that determines the capacity of a given area to meet habitat requirements for a specific species with respect to given variables. The degree of universality of this index is not well understood ye ...
2024Engineering novel protein interactions with therapeutic potential using deep learning-guided surface design
Proteins are foundational biomolecules of life playing a crucial role in a myriad of biological processes. Their function often requires interplay with other biomolecules, including proteins themselves. Protein-protein interactions (PPIs) are essential for ...
EPFL2024Invasive palms have more efficient and prolonged CO2 assimilation compared to native sub-Mediterranean vegetation
Charlotte Grossiord, Christoph Bachofen, Thibaut Michel Georges Juillard, Janisse Deluigi, Marco Conedera
In sub-Mediterranean ecosystems, shade-tolerant broadleaf evergreens, especially the invasive Trachycarpus fortunei, are spreading uncontrollably in the forest understorey, impeding the regeneration of the native deciduous woody vegetation. Most invasive s ...
Amsterdam2024Impact of phylogeny on structural contact inference from protein sequence data
Anne-Florence Raphaëlle Bitbol, Nicola Dietler, Umberto Lupo
Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins. They rely on correlations in amino acid usage at contacting sites. Because homologous proteins share a common ance ...
ROYAL SOC2023A benchmark dataset for machine learning in ecotoxicology
Kristin Schirmer, Marco Baity-Jesi, Fernando Perez Cruz
The use of machine learning for predicting ecotoxicological outcomes is promising, but underutilized. The curation of data with informative features requires both expertise in machine learning as well as a strong biological and ecotoxicological background, ...
Berlin2023Different responses of mice and rats hippocampus CA1 pyramidal neurons to in vitro and in vivo-like inputs
Ying Shi, Armando Romani, Michele Migliore, Maurizio Ferdinando Pezzoli, Rosanna Migliore
The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into individual output spikes. These spikes, in turn, act as inputs for other neurons in the network. Neurons must execute this function acro ...
2023Evaluation of genetic demultiplexing of single-cell sequencing data from model species
Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes. However, these technologies are expensive and require sufficient cell quantities and biological replicates to avoid artifactual results. An option to address thes ...
LIFE SCIENCE ALLIANCE LLC2023Digital reconstruction of the mammalian spinal cord: from anatomical reference volume to cell type atlas of the mouse spinal cord
The spinal cord is an elongated nervous structure that together with the brain forms the central nervous system. It relays sensory and motor information between the brain and the body, thus controlling most somatic and autonomic body functions. In recent y ...
EPFL2023Brain mitochondrial diversity and network organization predict anxiety-like behavior in male mice
The brain and behavior are under energetic constraints, limited by mitochondrial energy transformation capacity. However, the mitochondria-behavior relationship has not been systematically studied at a brain-wide scale. Here we examined the association bet ...
2023