Concept
Métabolome
Publications associées (67)
NMR and MS reveal characteristic metabolome atlas and optimize esophageal squamous cell carcinoma early detection
Lijing Xin, Yubo Zhao, Yan Lin, Wei Ye
Metabolic changes precede malignant histology. However, it remains unclear whether detectable characteristic metabolome exists in esophageal squamous cell carcinoma (ESCC) tissues and biofluids for early diagnosis. Here, we conduct NMR- and MS-based metabo ...
Nature Portfolio2024Innovative Biomarkers for Obesity and Type 1 Diabetes Based on Bifidobacterium and Metabolomic Profiling
Stephan Morgenthaler, Paul Refinetti, Mariya Yuryevna Skvortsova
The role of Bifidobacterium species and microbial metabolites such as short-chain fatty acids (SCFAs) and human milk oligosaccharides in controlling intestinal inflammation and the pathogenesis of obesity and type 1 diabetes (T1D) has been largely studied ...
MDPI2024An epidermal wearable microfluidic patch for simultaneous sampling, storage, and analysis of biofluids with counterion monitoring
Silvia Demuru, Brince Paul Kunnel
Simultaneous access to different biofluids enables an accurate analysis of multiple analytes, leading to a precision diagnosis and appropriate medication. Additionally, establishing a relationship between various markers in different biofluids and their co ...
ROYAL SOC CHEMISTRY2022Grape polyphenols decrease circulating branched chain amino acids in overfed adults
Jörg Hager, José Luis Abelleira Fernández, Sofia Moco
Introduction and aimsDietary polyphenols have long been associated with health benefits, including the prevention of obesity and related chronic diseases. Overfeeding was shown to rapidly induce weight gain and fat mass, associated with mild insulin resist ...
FRONTIERS MEDIA SA2022Assessing normalization methods in mass spectrometry-based proteome profiling of clinical samples
Background: Large-scale proteomic studies have to deal with unwanted variability, especially when samples originate from different centers and multiple analytical batches are needed. Such variability is typically added throughout all the steps of a clinica ...
ELSEVIER SCI LTD2022Late post‐natal neurometabolic development in healthy male rats using 1 H and 31 P Magnetic Resonance Spectroscopy
Rolf Gruetter, Cristina Ramona Cudalbu, Dunja Simicic, Veronika Rackayová, Guillaume Donati
Brain metabolism evolves rapidly during early post‐natal development in the rat. While changes in amino acids, energy metabolites, antioxidants or metabolites involved in phospholipid metabolism have been reported in the early stages, neurometabolic change ...
2021