Concept

Contraction musculaire

Publications associées (411)

Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)

Dimitri Nestor Alice Van De Ville, Theo Lasser, Kai Johnsson, Marcel Leutenegger, Boris Hinz, Iwan Märki, Thiemo Spielmann, Aurélie Formey de Saint Louvent

The measurement of tissue and cell oxygenation is important for understanding cell metabolism. We have addressed this problem with a novel optical technique, called triplet imaging, that exploits oxygen-induced triplet lifetime changes and is compatible wi ...

Elsevier2010

A New Lock-step Mechanism of Matrix Remodelling Based on Subcellular Contractile Events

Jean-Jacques Meister, Boris Hinz, Lara Buscemi Estefanell, Lysianne Follonier Castella

Myofibroblasts promote tissue contractures during fibrotic diseases. To understand how spontaneous changes in the intracellular calcium concentration, Ca2+, contribute to myofibroblast contraction, we analysed both Ca2+ and subcellular contractio ...

Company of Biologists2010

Intercellular coupling regulates the period of the segmentation clock

Andrew Charles Oates

Background: Coupled biological oscillators can tick with the same period. How this collective period is established is a key question in understanding biological clocks. We explore this question in the segmentation clock, a population of coupled cellular o ...

2010

Coordination of Myofibroblast Contraction in Vitro

Lysianne Follonier Castella

The aim of this thesis is to elucidate the common mechanisms that regulate myofibroblast contraction and intercellular communication, with a particular focus on the role of Ca2+ signalling. Synthesis and remodelling of collagenous matrix by myofibroblasts ...

EPFL2010

Regulation of myofibroblast activities: Calcium pulls some strings behind the scene

Boris Hinz, Lysianne Follonier Castella

Myofibroblast-induced remodeling of collagenous extracellular matrix is a key component of our body's strategy to rapidly and efficiently repair damaged tissues; thus myofibroblast activity is considered crucial in assuring the mechanical integrity of vita ...

Elsevier2010

Advanced Instrumentation For Measuring Fluid-Structure Coupling Phenomena In The Guide Vanes Cascade Of A Pump-Turbine Scale Model

François Avellan, Mohamed Farhat, Vlad Hasmatuchi, Steven Roth, Francisco Botero

In the present study, the fluid-structure coupling is investigated in the guide vanes cascade of a pump-turbine scale model placed in the EPFL PF3 test rig. The paper focuses on the advanced instrumentation used to get reliable and complete fluid-structure ...

American Soc Mechanical Engineers, Three Park Avenue, New York, Ny 10016-5990 Usa2010

Advanced Instrumentation for Measuring Fluid-Structure Coupling Phenomena in the Guide Vanes Cascade of a Pump-Turbine Scale Model

François Avellan, Mohamed Farhat, Vlad Hasmatuchi, Steven Roth, Francisco Botero

In the present study, the fluid-structure coupling is investigated in the guide vanes of a pump-turbine scale model placed in one of the test rigs of the Laboratory for Hydraulic Machines (EPFL) in Lausanne. The paper focuses on the advanced instrumentatio ...

American Soc Mechanical Engineers, Three Park Avenue, New York, Ny 10016-5990 Usa2010

A musculoskeletal shoulder model based on pseudo-inverse and null-space optimization

Dominique Pioletti, Denis Gillet, Alexandre Terrier, Alain Farron, Philippe Müllhaupt, Yvan Michellod, Martin Aeberhard

The goal of the present work was assess the feasibility of using a pseudo-inverse and null-space optimization approach in the modeling of the shoulder biomechanics. The method was applied to a simplified musculoskeletal shoulder model. The mechanical syste ...

Elsevier2010

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

Matthias Lütolf, Nora Leonardi

Freshly isolated muscle stem cells (MuSCs) exhibit robust regenerative capacity in vivo that is rapidly lost in culture. Using a bioengineered substrate to recapitulate key biophysical and biochemical niche features in conjunction with a novel highly autom ...

2010

Compressed collagen gel: a novel scaffold for human bladder cells

Florian Maria Wurm, Peter Frey, Jeffrey Alan Hubbell

Collagen is highly conserved across species and has been used extensively for tissue regeneration; however, its mechanical properties are limited. A recent advance using plastic compression of collagen gels to achieve much higher concentrations significant ...

Wiley-Blackwell2010

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