Concept

Pompe à insuline

Publications associées (121)

Design and Optimization of A Blood Pump for A Wearable Artificial Kidney Device

Yves Perriard, Miroslav Markovic, Michaël Rapin

The aim of the European project Nephron+ is the design of a wearable artificial kidney device. This paper is focused on the design of the corresponding ultralow-hemolysis continuous-operation blood pump. Accurate specifications and operating principle of t ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Prevention of Caval Collapse During Venous Drainage for CPB

Julien Favre

A new plastic self-expanding Smartcanula (Smartcanula LLC, Lausanne, Switzerland) is designed for central insertion and prevention of caval collapse. The objective of our work is to assess the influence of the new design on atrial chatter. Caval collapse o ...

Lippincott Williams & Wilkins2013

Restoration of direct pathway glycogen synthesis flux in the STZ-diabetes rat model by insulin administration

Ana Francisca Leal Silva Soares

Type 1 diabetes subjects are characterized by impaired direct pathway synthesis of hepatic glycogen that is unresponsive to insulin therapy. Since it is not known whether this is an irreversible defect of insulin-dependent diabetes, direct and indirect pat ...

2012

A Viscosity-Dependent Affinity Sensor for Continous Monitoring of Glucose in Biological Fluids

Christophe Boss

For fifty years, tremendous efforts have been directed towards the development of glucose sensors for tight glycemic control of diabetic patients. Today, millions of diabetics test their blood glucose level daily, making glucose the most commonly tested an ...

EPFL2012

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expenditure

Johan Auwerx, Kristina Schoonjans, Chikage Mataki

Besides well-established roles of bile acids (BA) in dietary lipid absorption and cholesterol homeostasis, it has recently become clear that BA is also a biological signaling molecule. We have shown that strategies aimed at activating TGR5 by increasing th ...

Public Library of Science2012

LRH-1-dependent glucose sensing determines intermediary metabolism in liver

Johan Auwerx, Kristina Schoonjans, Norman Lionel Moullan, Chikage Mataki, Hiroyasu Yamamoto, Taoufiq Harach, Maaike Hélène Oosterveer

Liver receptor homolog 1 (LRH-1), an established regulator of cholesterol and bile acid homeostasis, has recently emerged as a potential drug target for liver disease. Although LRH-1 activation may protect the liver against diet-induced steatosis and insul ...

American Society for Clinical Investigation2012

Design of a blood pump for a wearable artificial kidney device

Yves Perriard, Miroslav Markovic, Michaël Rapin

The aim of a European project Nephron+ is design of a wearable artificial kidney device (WAKD). This paper is focused on design of the corresponding ultralow-hemolysis continuous-operation blood pump. Accurate specifications and operating principle of the ...

Ieee2012

Preclinically assessed optimal control of postprandial glucose excursions for type 1 patients with diabetes

Denis Gillet, Grégory François, Alain Bock, Thierry Prud'Homme

Type 1 Patients with Diabetes (Type 1 PwDs) have to frequently adjust their insulin dosage to keep their Blood Glucose concentration (BG) within normal bounds. Meal intakes represent the most important disturbance that has to be accounted for. Its effect d ...

2011

JewelPUMP (TM) by Debiotech S.A.: Insulin Temperature Measurement Study

Adrien De Muralt

For type 1 Diabetes, insulin injection therapy is the most used treatment today, and insulin pumps are surely the most accurate therapeutic strategy. The insulin use temperature has to not exceed 37°C to prevent unwanted degradation and loss of function. T ...

2011

Flexprint substrate enzyme sensor for determination of daily glucose-profiles for diabetic patients

Nico de Rooij, Peter Van der Wal

The goal is to develop a miniaturized system allowing continuous measurement of glucose concentration profiles over 24 hours for several days. The unique feature of the PharmaSens / IMT approach lies in the insertion mechanism and the needle size to assure ...

2011

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