Concept

Évolution moléculaire

Publications associées (309)

A Quantitative Test of Hamilton's Rule for the Evolution of Altruism

Dario Floreano, Laurent Keller, Markus Waibel

The evolution of altruism is a fundamental and enduring puzzle in biology. In a seminal paper Hamilton showed that altruism can be selected for when rb − c>0, where c is the fitness cost to the altruist, b is the fitness benefit to the beneficiary, and r i ...

Public Library of Science2011

Genetic Mouse Models of Neurodegenerative Diseases

Darren Moore, Alzbeta Trancikova, David Ramonet Jimenez

Neurodegenerative diseases are generally characterized by the selective degeneration of particular neuronal populations and the accumulation of abnormal or aggregated proteins within, but occasionally external to, neurons in affected brain regions. These d ...

2011

Collisional damping of dipole oscillations in a trapped polariton gas

Benoît Marie Joseph Deveaud, François Morier-Genoud, Marcia Portella Oberli, Barbara Pietka, Taofiq Paraïso, Roland Cerna

We study the relaxation dynamics of a trapped polariton gas in the nonlinear regime. We excite the three lowest energy states of the system and observe the time evolution of the polariton density in the momentum space. At a low excitation power, the dynami ...

2011

Analysis of Co-evolving Gene Families Using Mutually Exclusive Orthologous Modules

Xiuwei Zhang

Coevolutionary networks can encapsulate information about the dynamics of presence and absence of gene families in organisms. Analysis of such networks should reveal fundamental principles underlying the evolution of cellular systems and the functionality ...

2011

A regulatory archipelago controls hox genes transcription in digits

Denis Duboule

The evolution of digits was an essential step in the success of tetrapods. Among the key players, Hoxd genes are coordinately regulated in developing digits, where they help organize growth and patterns. We identified the distal regulatory sites associated ...

2011

Coherent oscillations between polariton vortex and anti-vortex states in an elliptical resonator

Benoît Marie Joseph Deveaud, Gaël Nardin, François Morier-Genoud, Barbara Pietka

In this experimental work, we optically excite the eigenmodes of an elliptical resonator in a semiconductor micro-cavity. Using a pulsed excitation, we create a superposition of eigenmodes, and image the time evolution of the coherent emission pattern. Osc ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2011

Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

Craig Nowell, Xin Jin

The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and molecular basis of Foxn1 function, we gener ...

Public Library of Science2011

Environment - Application - Adaptation: a Community Architecture for Ambient Intelligence

Rémi Emonet

This article considers the software problems of reuse, interoperability and evolution in the context of Ambient Intelligence. A novel approach is introduced: the Environment, Application, Adaptation (EAA) is streamlined for Ambient Intelligence and is evol ...

2011

Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain

Doris Chau Voo Thu

Human diseases are often accompanied by histological changes that confound interpretation of molecular analyses and identification of disease-related effects. We developed population-specific expression analysis (PSEA), a computational method of analyzing ...

Nature Publishing Group2011

A bifunctional organometallic ruthenium drug with multiple modes of inducing apoptosis

Paul Joseph Dyson, Ilaria Biondi

The organometallic glutathione S-transferase inhibitor ruthenium(II) (ethacrynic acid-η6-benzylamide)(1,3,5-triaza-7-phosphaadamantane) dichloride, termed ethaRAPTA, has been demonstrated to induce apoptosis in the cisplatin-resistant MCF-7 breast cancer c ...

2011

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