Publications associées à Épigénomique

Gene regulatory mechanisms underlying the intestinal innate immune response

Bart Deplancke, Antonio Carlos Alves Meireles Filho

In the mammalian gastrointestinal tract, distinct types of cells, including epithelial cells and macrophages, collaborate to eliminate ingested pathogens while striving to preserve the commensal microbiota. The underlying innate immune response is driven b ...

Elsevier2017

Meta-analysis of incomplete microarray studies

Anthony Christopher Davison, Darlene Goldstein

Meta-analysis of microarray studies to produce an overall gene list is relatively straightforward when complete data are available. When some studies lack information, for example, having only a ranked list of genes instead of complete primary data, it is ...

Oxford University Press2015

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

Jacques Rougemont, Philippe Jacquet

Previous studies indicate that eukaryotic promoters display a stereotypical chromatin landscape characterized by a well-positioned +1 nucleosome near the transcription start site and an upstream 1 nucleosome that together demarcate a nucleosome-free (or -d ...

Elsevier2015

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data

Bart Deplancke, Sebastian Martin Waszak, Sunil Kumar Raghav, Nouria Hernandez, Alisa Yurovsky

Motivation: High-throughput sequencing technologies enable the genome-wide analysis of the impact of genetic variation on molecular phenotypes at unprecedented resolution. However, although powerful, these technologies can also introduce unexpected artifac ...

Oxford University Press2014

Evolutionary dynamics of coding and non-coding transcriptomes

Anamaria Necsulea

Gene expression changes may underlie much of phenotypic evolution. The development of high-throughput RNA sequencing protocols has opened the door to unprecedented large-scale and cross-species transcriptome comparisons by allowing accurate and sensitive a ...

Nature Publishing Group2014

Principles of ChIP-seq Data Analysis Illustrated with Examples

Giovanna Ambrosini, Philipp Bucher, René Dreos

Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) is a powerful method to determine how transcription factors and other chromatin-associated proteins interact with DNA in order to regulate gene transcription. A single C ...

Copicentro Granada S L2014

Two distinct promoter architectures centered on dynamic nucleosomes control ribosomal protein gene transcription

Felix Naef, Sebastian Maerkl, Jacques Rougemont, Nicolas Dénervaud, Marcel Geertz, Philippe Jacquet

In yeast, ribosome production is controlled transcriptionally by tight coregulation of the 138 ribosomal protein genes (RPGs). RPG promoters display limited sequence homology, and the molecular basis for their coregulation remains largely unknown. Here we ...

Cold Spring Harbor Laboratory Press2014

Programming and use of Parylene C fluorescence as a quantitative on-chip reference

Martinus Gijs, Diego Gabriel Dupouy, Ata Tuna Ciftlik, Joan Teixidor

A large number of lab-on-a-chip applications use fluorescence for quantifying biological entities. In such applications, incorporation of a stable on-chip fluorescent reference source would be highly desirable in order to compensate for instrumental parame ...

Royal Soc Chemistry2014

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Épigénomique

Gene regulatory mechanisms underlying the intestinal innate immune response

Meta-analysis of incomplete microarray studies

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

Multi-scale landscape genomic models

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data

Computational studies in epigenomics using histone modification data

Evolutionary dynamics of coding and non-coding transcriptomes

Principles of ChIP-seq Data Analysis Illustrated with Examples

Two distinct promoter architectures centered on dynamic nucleosomes control ribosomal protein gene transcription

Programming and use of Parylene C fluorescence as a quantitative on-chip reference

Graph Chatbot

Chattez avec Graph Search

Computational studies in epigenomics using histone modification data

Multi-scale landscape genomic models

Meta-analysis of incomplete microarray studies

Gene regulatory mechanisms underlying the intestinal innate immune response

Identification and removal of low-complexity sites in allele-specific analysis of ChIP-seq data

Evolutionary dynamics of coding and non-coding transcriptomes

Two distinct promoter architectures centered on dynamic nucleosomes control ribosomal protein gene transcription

Programming and use of Parylene C fluorescence as a quantitative on-chip reference

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

Principles of ChIP-seq Data Analysis Illustrated with Examples