Publications associées à Upper motor neuron

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

Auke Ijspeert, Robin Thandiackal

An important topic in designing neuroprosthetic devices for animals or patients with spinal cord injury is to find the right brain regions with which to interface the device. In vertebrates, an interesting target could be the reticulospinal (RS) neurons, w ...

IEEE2016

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease

Hilal Lashuel, Bohumil Maco, Abid Oueslati, Mohamed Bilal Fares

Lewy bodies (LBs) are intraneuronal inclusions consisting primarily of fibrillized human α-synuclein (hα-Syn) protein, which represent the major pathological hallmark of Parkinson's disease (PD). Although doubling hα-Syn expression provokes LB pathology in ...

Natl Acad Sciences2016

Simulation Neurotechnologies for Advancing Brain Research: Parallelizing Large Networks in NEURON

Felix Schürmann, Michael Lee Hines

Large multiscale neuronal network simulations are of increasing value as more big data are gathered about brain wiring and organization under the auspices of a current major research initiative, such as Brain Research through Advancing Innovative Neurotech ...

Mit Press2016

Cortical neurons gradually attain a post-mitotic state

Johannes Gräff

Once generated, neurons are thought to permanently exit the cell cycle and become irreversibly differentiated. However, neither the precise point at which this post-mitotic state is attained nor the extent of its irreversibility is clearly defined. Here we ...

Inst Biochemistry & Cell Biology2016

Improvement in precision grip force control with self-modulation of primary motor cortex during motor imagery

Roger Gassert, Maria Laura Blefari

Motor imagery (MI) has shown effectiveness in enhancing motor performance. This may be due to the common neural mechanisms underlying MI and motor execution (ME). The main region of the ME network, the primary motor cortex (M1), has been consistently linke ...

Frontiers Research Foundation2015

Parallel pathways from motor and somatosensory cortex for controlling whisker movements in mice

Carl Petersen, Varun Sreenivasan

Mice can gather tactile sensory information by actively moving their whiskers to palpate objects in their immediate surroundings. Whisker sensory perception therefore requires integration of sensory and motor information, which occurs prominently in the ne ...

Wiley-Blackwell2015

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Bernard Schneider, Céline Ruegsegger, Niran Maharjan

Mechanisms underlying motor neuron subtype selective endoplasmic reticulum (ER) stress and associated axonal pathology in amyotrophic lateral sclerosis (ALS) remain unclear. Here we show that the molecular environment of the ER between motor neuron subtype ...

Nature Publishing Group2015

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Roman Chrast, Nathalie Marie Géraldine Bernard

Mutations in SIGMAR1, which encodes the Sigma 1 receptor, cause a familial form of amyotrophic lateral sclerosis, but the underlying molecular mechanisms are unclear. Bernard-Marissal et al. reveal that disruption of Sigma 1 receptor function disturbs endo ...

Oxford University Press2015

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Upper motor neuron

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease

Spectral Variability in the Aged Brain during Fine Motor Control

Simulation Neurotechnologies for Advancing Brain Research: Parallelizing Large Networks in NEURON

Cortical neurons gradually attain a post-mitotic state

Improvement in precision grip force control with self-modulation of primary motor cortex during motor imagery

Parallel pathways from motor and somatosensory cortex for controlling whisker movements in mice

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Regulation of Cortical Dynamic Range by Background Synaptic Noise and Feedforward Inhibition

Graph Chatbot

Chattez avec Graph Search

Cortical neurons gradually attain a post-mitotic state

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

Simulation Neurotechnologies for Advancing Brain Research: Parallelizing Large Networks in NEURON

Improvement in precision grip force control with self-modulation of primary motor cortex during motor imagery

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Parallel pathways from motor and somatosensory cortex for controlling whisker movements in mice

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Spectral Variability in the Aged Brain during Fine Motor Control

Regulation of Cortical Dynamic Range by Background Synaptic Noise and Feedforward Inhibition