Concept
Bacillus anthracis
Publications associées (37)
S-acylation and lipid exchange at the ER-Golgi membrane contact sites regulate pathogen entry in human cells
Cells have evolved endocytic pathways to internalize different molecules, to regulate intra-cellular communication and their interaction with external environment. Pathogens have co-evolved with cells to exploit these processes for infections. In particula ...
EPFL2024Genomic and metabolic adaptations of biofilms to ecological windows of opportunity in glacier-fed streams
Tom Ian Battin, Hannes Markus Peter, Susheel Bhanu Busi, Grégoire Marie Octave Edouard Michoud, Leïla Ezzat, Massimo Bourquin, Tyler Joe Kohler, Stylianos Fodelianakis, Paraskevi Pramateftaki, Vincent Henri De Staercke, Matteo Tolosano, Michail Styllas, Martina Andrea Schön
In glacier-fed streams, ecological windows of opportunity allow complex microbial biofilms to develop and transiently form the basis of the food web, thereby controlling key ecosystem processes. Using metagenome-assembled genomes, we unravel strategies tha ...
Springer2022Photodynamic treatment of multidrug-resistant bacterial infection using indium phosphide quantum dots
Francesco Stellacci, Inyoung Yonah Lee
Infections caused by multidrug-resistant (MDR) bacteria pose an impending threat to humanity, as the evolution of MDR bacteria outpaces the development of effective antibiotics. In this work, we use indium phosphide (InP) quantum dots (QDs) to treat infect ...
ROYAL SOC CHEMISTRY2022Analysis of a bac operon-silenced strain suggests pleiotropic effects of bacilysin in Bacillus subtilis
Bacilysin, as the simplest peptide antibiotic made up of only L-alanine and L-anticapsin, is produced and excreted by Bacillus subtilis under the control of quorum sensing. We analyzed bacilysin-nonproducing strain OGU1 which was obtained by bacA-targeted ...
MICROBIOLOGICAL SOCIETY KOREA2020Loss of Bacterial Cell Pole Stabilization in Caulobacter crescentus Sensitizes to Outer Membrane Stress and Peptidoglycan-Directed Antibiotics
Gerardo Turcatti, Marc Chambon, Julien Bortoli Chapalay
Rod-shaped bacteria frequently localize proteins to one or both cellpoles in order to regulate processes such as chromosome replication or polar organ-elle development. However, the roles of polar factors in responses to extracellularstimuli have been gene ...
2020Chromate tolerance and removal of bacterial strains isolated from uncontaminated and chromium-polluted environments
Rizlan Bernier-Latmani, Imrich Barak, Zuzana Chromiková
Investigation of bacterial chromate tolerance has mostly focused on strains originating from polluted sites. In the present study, we isolated 33 chromate tolerant strains from diverse environments harbouring varying concentrations of chromium (Cr). All of ...
2019Anthrax toxin requires ZDHHC5-mediated palmitoylation of its surface-processing host enzymes
Françoise Gisou van der Goot Grunberg, Oksana Andrei Sergeeva
The protein acyl transferase ZDHHC5 was recently proposed to regulate trafficking in the endocytic pathway. Therefore, we explored the function of this enzyme in controlling the action of bacterial toxins. We found that ZDHHC5 activity is required for two ...
2019More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis
Tuberculosis (TB), whose etiological agent is Mycobacterium tuberculosis (M. tuberculosis), has plagued humanity since antiquity. Even with chemotherapy available today, TB is the leading cause of death due to an infectious disease. Modern day factors, suc ...
EPFL2018