Concept

Ion-mobility spectrometry–mass spectrometry

Publications associées (403)

Conformation of Polyalanine and Polyglycine Dications in the Gas Phase: Insight from Ion Mobility Spectrometry and Replica-Exchange Molecular Dynamics

Yury Tsybin, Aleksey Vorobyev, Rodolphe Antoine

The conformation of model Arg(Ala)(4)X(Ala)(4)Lys+2H and Arg(Gly)(4)X(Gly)(4)Lys+2H peptides has been systematically investigated as a function of the central amino acid X through a combined experimental and theoretical approach. Mass spectrome ...

American Chemical Society2010

Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples

Luiz Felippe De Alencastro

Several interlaboratory exercises were organised within the framework of European FP6 project NOR-MAN Among others. non-steroidal anti-inflammatory drugs were investigated in different aqueous samples in two sequential ring studies. The aim of both studies ...

Elsevier2010

Electrochemical Aspects of Electrospray and Laser Desorption/Ionization for Mass Spectrometry

Hubert Girault, Liang Qiao, Mélanie Abonnenc

Soft-ionization methods, namely electrospray ionization and laser desorption/ionization, are widely used to transfer large molecules as intact gas-phase ions either from a solution or from a solid substrate. During both processes, in-source electrochemical ...

2010

Copper(I) and copper(II) binding to β-amyloid 16 (Aβ16) studied by electrospray ionization mass spectrometry

Hubert Girault, Liang Qiao, Michel Prudent, Yu Lu

Copper-b-amyloid 16 (Aβ16) complexes were investigated by electrospray ionization mass spectrometry (ESI-MS). Copper(I) and (II) complexes were formed on-line in a microchip electrospray emitter by using a sacrificial copper electrode as the anode in posit ...

Royal Society of Chemistry2010

Mass Spectrometry Based Analysis and Bioanalysis

Hongyan Bi

MS (mass spectrometry) has been developed as an important analytical tool to study large molecules including polymer macromolecules and proteins. Its instrumentation technique including ionization methods, mass analyzer and detector systems has been greatl ...

EPFL2010

Interactome and reverse genetics studies of regulatory subunits of Plasmodium falciparum casein kinase

Guillem Dayer

Malaria is the most devastating parasitic infection killing each year between 1 and 3 million of people. Furthermore this decease has a huge socio-economic impact in affected countries. The emergence of resistance against currently used drug makes the deve ...

2010

A new tandem mass spectrometer for photofragment spectroscopy of cold, gas-phase molecular ions

Thomas Rizzo, Ulrich Lorenz, Annette Svendsen

We present here the design of a new tandem mass spectrometer that combines an electrospray ion source with a cryogenically cooled ion trap for spectroscopic studies of cold, gas-phase ions. The ability to generate large ions in the gas phase without fragme ...

American Institute of Physics2010

Insights on EVA lamination process: Where do the bubbles come from?

Christophe Ballif, Hengyu Li, Laure-Emmanuelle Perret Aebi

• The identification and control of volatile organic compounds (VOCs) released by polymers during lamination in the photovoltaic (PV) industry is of considerable importance to establish and optimize processes in order to ensure a long term reliability of t ...

2010

Reactivity of anticancer metallodrugs with serum proteins: New insights from size exclusion chromatography-ICP-MS and ESI-MS

Paul Joseph Dyson, Angela Casini, Michael Groessl

A method based on the coupling of high resolution size-exclusion liquid chromatography using a polymer stationary phase with inductively coupled plasma mass spectrometry was developed to study the interactions of two metallodrugs - cisplatin and RAPTA-T - ...

Royal Society of Chemistry2010

Drug delivery of lipophilic pyrenyl derivatives by encapsulation in a water soluble metalla-cage

Paul Joseph Dyson, Olivier Pierre Zava, Anna Katherine Renfrew

The self-assembly of 2,4,6-tris(pyridin-4-yl)-1,3,5-triazine (tpt) triangular panels with p-cymene (p-PriC6H4Me) ruthenium building blocks and 2,5-dioxydo-1,4-benzoquinonato (dobq) bridges, in the presence of a functionalized pyrenyl deriv. (pyrene-R), aff ...

Royal Society of Chemistry2010

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