Concept

Hydroxyapatite

Publications associées (39)

The effect of bisphosphonates and titanium particles on osteoblasts: an in vitro study

In an attempt to increase the life of cementless prostheses, an hydroxyapatite-coated implant which releases a bisphosphonate has been suggested as a drug-delivery system. Our in vitro study was designed to determine the maximum dose to which osteoblasts c ...

2005

Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration

Dominique Pioletti, Bastian Peter

Despite total hip replacement (THR) gives generally satisfactory results, the quality of outcome in young patients is markedly decreased compared to the average THR outcome. For this population, pharmacological treatment with bisphosphonate would be benefi ...

2005

HRTEM simulation in determination of thickness and grain misorientation for hydroxyapatite crystals

Philippe Buffat, Pierre Stadelmann, Elena Suvorova Buffat

High-resolution transmission electron microscopy (HRTEM) and HRTEM simulation by the Bloch wave method (JEMS) are used to determine the structure and thickness of micro- and nanocrystals of biominerals and hydroxyapatite grown from aqueous solutions. It is ...

2004

Properties of the elastic anomaly in SrBi2Nb2O9-based ceramics

Nava Setter, Dragan Damjanovic

A study was conducted on the effects of compositional modifications on the temperature coefficient of resonance frequency (TCF) in the disc planar vibration mode for the bismuth layer-structured compound SrBi2Nb2O9 (SBN)-based ceramics. The substitution of ...

2003

A calcium phosphate implant with controlled macroporosity for anterior L5-S1 interbody fusion

In the United States approximately 50 million people suffer from low back pain. In the 20-50 years age group, this is the most important and expensive health care problem. The causes of low back pain are various. A herniated disk or spinal stenosis may tra ...

EPFL2002

Size effect in X-ray and electron diffraction patterns from hydroxyapatite particles

Philippe Buffat, Elena Suvorova Buffat

High-resolution transmission electron microscopy (HRTEM), electron microdiffraction, and X-ray diffraction were used to study hydroxyapatite specimens with particle sizes from a few nanometers to several hundreds of nanometers. Diffuse scattering (without ...

2001

The effects of calcium phosphate cement particles on osteoblast functions

Dominique Pioletti, Pascale Van Landuyt

Calcium phosphate cements (CPC) are increasingly used in the orthopedic field. This kind of cement has potential applications in bone defect replacements, osteosynthetic screw reinforcements or drug delivery. In vivo studies have demonstrated a good osteoi ...

2000

Immobilization of uranium in contaminated sediments by hydroxyapatite addition

Jeremy Samuel Arey

Batch equilibrations were performed to investigate the ability of hydroxyapatite (Ca5(PO4)3OH) to chemically immobilize U in two contaminated sediment samples having different organic carbon contents (123 and 49 g kg-1, respectively). Apatite additions low ...

1999

Ceramic hydroxyapatite: a new tool for separation and analysis of IgA monoclonal antibodies

Urs von Stockar, Ian William Marison

A novel downstream process is reported for preparative scale prodn. of dimeric IgA, a protein with potential pharmaceutical applications. Time-consuming size exclusion chromatog. was replaced by ceramic hydroxyapatite chromatog. (CHT). A clear baseline sep ...

1997

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