Concept

Placebo-controlled study

Publications associées (82)

Development of Minimally-Invasive Optical Methods to Individualize the Doses Used for Therapeutic Applications of Light

Despite the experience gained over several decades in various types of light-based medical treatments, the optimization of the corresponding therapeutic protocols and accurate forecasting of their outcome have not yet been achieved in many cases. The diffi ...

EPFL2010

Cardiac ablation, How Contact Force influences lesion quality

Olivier Frémont

Cardiac ablation is a worldwide accepted minimally invasive procedure to treat Atrial Fibrillation (AF). It consists in creating lesions with a catheter in the cardiac tissue in order to cut off specific electrical pathways. During this project, based on p ...

2010

Autofluorescence bronchoscopy: quantification of inter-patient variations of fluorescence intensity

Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht, Blaise Lovisa

Autofluorescence (AF) from bronchial tissue is increasingly used for the endoscopic detection of early bronchial neoplasia. Several imaging systems are commercially available, all detecting the absolute or relative AF intensity and/or spectral contrasts be ...

Springer-Verlag2009

A Surface-based approach to Quantify Local Cortical Gyrification

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer, François Lazeyras

The high complexity of cortical convolutions in humans remains a mystery for both engineers to measure and compare it, and for biologists to understand it. We developed a method for the quantification of the cortical area allowed by the process of folding. ...

2008

Effects of brain polarization on reaction times and pinch force in chronic stroke

Friedhelm Christoph Hummel

Previous studies showed that anodal transcranial DC stimulation (tDCS) applied to the primary motor cortex of the affected hemisphere (M1affected hemisphere) after subcortical stroke transiently improves performance of complex tasks that mimic activities o ...

BioMed Central2006

Analysis of gait and coordination for arthroplasty outcome evaluation using body-fixed sensors

Hooman Dejnabadi

The importance of evaluation of an orthopedic operation such as hip or knee arthroplasty has long been recognized. Many definitions of outcome and scoring questionnaires have been used in the past to assess the outcome of joint replacement. However, these ...

EPFL2006

Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model

Hubert van den Bergh, Georges Wagnières, Elodie Debefve

The objective of this study was to evaluate the ability of meso-tetra(hydroxyphenyl)chlorin (m-THPC) encapsulated into liposomal formulations to occlude neovascularization. Two m-THPC formulations including conventional or plain liposomes (Foslip) based on ...

Elsevier2006

Dopaminergic influences on formation of a motor memory

Friedhelm Christoph Hummel

The ability of the central nervous system to form motor memories, a process contributing to motor learning and skill acquisition, decreases with age. Dopaminergic activity, one of the mechanisms implicated in memory formation, experiences a similar decline ...

Wiley-Blackwell2005

Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke

Friedhelm Christoph Hummel

Stroke is a leading cause of adult motor disability. Despite recent progress, recovery of motor function after stroke is usually incomplete. This double blind, Sham-controlled, crossover study was designed to test the hypothesis that non-invasive stimulati ...

Oxford University Press2005

Brain glucose concentrations in healthy humans subjected to recurrent hypoglycemia

Rolf Gruetter, Anjali Kumar

Mechanisms responsible for hypoglycemia unawareness remain unknown. Previously, we found that patients with type 1 diabetes and hypoglycemia unawareness had increased brain glucose concentrations as measured by (1)H-magnetic resonance spectroscopy (MRS) co ...

Wiley-Blackwell2005

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