Concept
Bacterial cellular morphologies
Publications associées (89)
Simple optical nanomotion method for single-bacterium viability and antibiotic response testing
Sandor Kasas, María Inés Villalba, Allan Bonvallat, Eugenia Rossetti
Antibiotic resistance is nowadays a major public health issue. Rapid antimicrobial susceptibility tests (AST) are one of the options to fight this deadly threat. Performing AST with single-cell sensitivity that is rapid, cheap, and widely accessible, is ch ...
NATL ACAD SCIENCES2023Functional characterization of Drosophila melanogaster immune effectors
Drosophila melanogaster, commonly known as the "fruit fly", is a genetically tractable model organism widely used to study biological processes, notably the innate immune system. The advent of novel genome editing technologies, such as the CRISPR-Cas9 syst ...
EPFL2023In vitro synergistic action of TAT-RasGAP 317-326 peptide with antibiotics against Gram-negative pathogens
Objectives: Multidrug-resistant (MDR) bacteria are a continuously increasing threat for medicine, caus-ing infections recalcitrant to antibiotics. Antimicrobial peptides (AMPs) were identified as alternatives to antibiotics, being naturally occurring short ...
ELSEVIER SCI LTD2022A systematic CRISPR approach to understanding the role of Drosophila antimicrobial peptides in immunity in vivo
Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading microbes. These short immune effectors are conserved in plants, animals, and fungi. Early work showed that AMPs killed bacteria in generalist fashions in vitro: i.e. AMPs that ...
EPFL2022