Publications associées à Enantiopure drug

Near-Enantiopure Trimerization of 9-Ethynylphenanthrene on a Chiral Metal Surface

Harald Brune, Roland Widmer, Aliaksandr Yakutovich, Jan Prinz, Samuel Thomas Stolz

Enantioselectivity in heterogeneous catalysis strongly depends on the chirality transfer between catalyst surface and all reactants, intermediates, and the product along the reaction pathway. Herein we report the first enantioselective on-surface synthesis ...

2020

In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-C-13]alanine

Rolf Gruetter, Hikari Ananda Infinity Yoshihara, Alice Radaelli

d-amino acid oxidase (DAO) is a peroxisomal enzyme that catalyzes the oxidative deamination of several neutral and basic d-amino acids to their corresponding alpha-keto acids. In most mammalian species studied, high DAO activity is found in the kidney, liv ...

2020

Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis

Nicolai Cramer, Benoît Daniel Bertrand Audic

The creation of new chiral ligands capable of providing high stereocontrol in metal-catalyzed reactions is crucial in modern organic synthesis. The production of bioactive molecules as single enantiomers is increasingly required, and asymmetric catalysis w ...

WILEY-V C H VERLAG GMBH2020

Interplay of H-Bonds with Aromatics in Isolated Complexes Identifies Isomeric Carbohydrates

Vladimir Kopysov, Ruslan Yamaletdinov, Aleksandr Pereverzev

The tremendous isomeric diversity of carbohydrates enables a wide range of their biological functions but makes the identification and study of these molecules difficult. We investigated the ability of intermolecular interactions to communicate structural ...

WILEY-V C H VERLAG GMBH2019

Accessible Superchiral Near-Fields Driven by Tailored Electric and Magnetic Resonances in All-Dielectric Nanostructures

Hatice Altug, Andreas Tittl, Yasaman Jahani, Kosmas Tsakmakidis, Ershad Mohammadi

Detection and differentiation of enantiomers in small quantities are crucially important in many scientific fields, including biology, chemistry, and pharmacy. Chiral molecules manifest their handedness in their interaction with the chiral state of light ( ...

AMER CHEMICAL SOC2019

Nanophotonic Platforms for Enhanced Chiral Sensing

Hatice Altug, Kosmas Tsakmakidis, Ershad Mohammadi

Chirality plays an essential role in life, providing unique functionalities to a wide range of biomolecules, chemicals, and drugs, which makes chiral sensing and analysis critically important. The wider application of chiral sensing continues to be constra ...

2018

Enantioselective Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds

Jérôme Waser, Durga Prasada Rao Hari

Enantioselective catalytic methods allowing the addition of both a nucleophile and an electrophile onto diazo compounds give a fast access into important building blocks. Herein, we report the highly enantioselective oxyalkynylation of diazo compounds usin ...

2017

Epitaxy-Induced Assembly and Enantiomeric Switching of an On-Surface Formed Dinuclear Organocobalt Complex

Harald Brune, Zhi Chen

We report on the surface-guided synthesis of a dinuclear organocobalt complex, its self-assembly into a complex nanoarchitecture, and a single-molecule level investigation of its switching behavior. Initially, an organic layer is prepared by depositing hex ...

American Chemical Society2017

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Enantiopure drug

Near-Enantiopure Trimerization of 9-Ethynylphenanthrene on a Chiral Metal Surface

In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-C-13]alanine

Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis

Interplay of H-Bonds with Aromatics in Isolated Complexes Identifies Isomeric Carbohydrates

X-ray Raman optical activity of chiral molecules

Accessible Superchiral Near-Fields Driven by Tailored Electric and Magnetic Resonances in All-Dielectric Nanostructures

Nanophotonic Platforms for Enhanced Chiral Sensing

Enantioselective Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds

Epitaxy-Induced Assembly and Enantiomeric Switching of an On-Surface Formed Dinuclear Organocobalt Complex

Graph Chatbot

Chattez avec Graph Search

Epitaxy-Induced Assembly and Enantiomeric Switching of an On-Surface Formed Dinuclear Organocobalt Complex

Accessible Superchiral Near-Fields Driven by Tailored Electric and Magnetic Resonances in All-Dielectric Nanostructures

Interplay of H-Bonds with Aromatics in Isolated Complexes Identifies Isomeric Carbohydrates

Near-Enantiopure Trimerization of 9-Ethynylphenanthrene on a Chiral Metal Surface

Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis

Enantioselective Copper-Catalyzed Oxy-Alkynylation of Diazo Compounds

X-ray Raman optical activity of chiral molecules

In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-C-13]alanine

Nanophotonic Platforms for Enhanced Chiral Sensing