Concept

Saccharomyces cerevisiae

Publications associées (162)

Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States

Telomerase counteracts telomere erosion that stems from incomplete chromosome end replication and nucleolytic processing. A precise understanding of telomere length homeostasis has been hampered by the lack of assays that delineate the nonuniform telomere ...

2004

A role for the Cdc14-family phosphatase Flp1p at the end of the cell cycle in controlling the rapid degradation of the mitotic inducer Cdc25p in fission yeast

Viesturs Simanis

The Schizosaccaromyces pombe protein Flp1p belongs to a conserved family of serine-threonine-phosphatases. The founding member of this family, Saccharomyces cerevisiae Cdc14p, is required for inactivation of mitotic CDKs and reversal of CDK mediated phosph ...

2004

Immobilization as a tool to control fermentation in yeast-leavened refrigerated dough

Urs von Stockar, Ian William Marison, Véronique Breguet, Raphaël Gugerli

In order to extend the shelf life of refrigerated dough, a new method based on thermo-gelling immobilization is proposed. This slows fermn. at low temps. (

2004

Induced Protein Dimerization in Vivo through Covalent Labeling

Kai Johnsson

The authors present here a novel approach to induce protein dimerization in living cells through covalent labeling of fusion proteins with ligands which are interacting with other proteins. The covalent labeling is based on the reaction of the DNA repair p ...

2003

Generally applicable fed-batch culture concept based on the detection of metabolic state by on-line balancing

Urs von Stockar, Ian William Marison, Christoph Herwig, Bernhard Walker

In many microorganisms, flux limitations in oxidative metab. lead to the formation of overflow metabolites even under fully aerobic conditions. This can be avoided if the specific growth rate is controlled at a low enough value. This is usually accomplishe ...

2003

Inhibition aspects of the bioconversion of L-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae

Urs von Stockar, Ian William Marison, Diana Zala

The inhibitory impacts of the bioconversion of L-phenylalanine (L-Phe) to 2-phenylethanol (PEA), a very important natural aroma compd., on the metab. of Saccharomyces cerevisiae Giv 2009 were investigated in batch and chemostat cultures. The bioconversion ...

2003

A human homolog of yeast est1 associates with telomerase and uncaps chromosome ends when overexpressed

Joachim Lingner, Philipp Bucher

Telomeres protect the eukaryotic chromosome ends from degradation and fusion. They are maintained by the ribonucleoprotein telomerase, the core of which is composed of a reverse transcriptase (TERT) and a RNA subunit. In the yeast Saccharomyces cerevisiae, ...

2003

Quantitative comparison of transient growth of Saccharomyces cerevisiae, Saccharomyces kluyveri, and Kluyveromyces lactis

Urs von Stockar, Christoph Herwig

A multitude of metabolic regulations occur in yeast, particularly under dynamic process conditions, such as under sudden glucose excess. However, quantification of regulations and classification of yeast strains under these conditions have yet to be elucid ...

2003

Telomere maintenance in fission yeast requires an Est1 ortholog

Philipp Bucher

Telomerase regulation is critical to genome maintenance yet remains poorly understood. Without telomerase's ability to synthesize telomere repeats, chromosome ends shorten progressively, as conventional DNA polymerases cannot fully replicate the ends of li ...

2003

xxvel type of in situ extraction: Use of solvent containing microcapsules for the bioconversion of 2-phenylethanol from L-phenylalanine by Saccharomyces cerevisiae

Urs von Stockar, Ian William Marison, Henri Kornmann

A novel in situ product removal (ISPR) method that uses microcapsules to ext. inhibitory products from the reaction suspension is introduced into fermn. technol. More specifically, L-phenylalanine (L-phe) was transformed by Saccharomyces cerevisiae to 2-ph ...

2003

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