Publications associées à Chromatographie en phase liquide-spectrométrie de masse

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu, Giulio Gambarota

OBJECT: To determine the single spin-echo T 2 relaxation times of uncoupled and J-coupled metabolites in rat brain in vivo at 14.1 T and to compare these results with those previously obtained at 9.4 T. MATERIALS AND METHODS: Measurements were performed on ...

Springer Verlag2013

Desiccation shrinkage of non-clayey soils: a numerical study

Lyesse Laloui, Hervé Péron

A meso-scale model based on the evolution of the pore system and idealized as bimodal is numerically examined. A simplified evolution of the model reveals a series of characteristics that qualitatively agree with the observed macroscopic experimental findi ...

Wiley-Blackwell2013

On the Utility of Isotopic Fine Structure Mass Spectrometry in Protein Identification

Yury Tsybin, Anton Kozhinov, Sasa Miladinovic

Modern mass spectrometry (MS)-based protein identification and characterization relies upon accurate mass measurements of the C-13 isotopic distributions of the enzymatically produced peptides. Interestingly, obtaining peptide elemental composition informa ...

2012

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

Yury Tsybin, Luca Fornelli

The primary structural information of proteins employed as biotherapeutics is essential if one wishes to understand their structure-function relationship, as well as in the rational design of new therapeutics and for quality control. Given both the large s ...

Amer Soc Biochemistry Molecular Biology Inc2012

In-Spray Supercharging of Peptides and Proteins in Electrospray Ionization Mass Spectrometry

Hubert Girault, Yury Tsybin, Luca Fornelli, Yu Lu, Sasa Miladinovic, Krzysztof Marek Piech

Enhanced charging, or supercharging, of analytes in electrospray ionization mass spectrometry (ESI MS) facilitates high resolution MS by reducing an ion mass-to-charge (m/z) ratio, increasing tandem mass spectrometry (MS/MS) efficiency. ESI MS superchargin ...

2012

Desorption of alkali atoms from 4He nanodroplets

Marcel Drabbels, Evgeniy Loginov, Marina Langlet

The dynamics following the photoexcitation of Na and Li atoms located on the surface of helium nanodroplets has been investigated in a joint experimental and theoretical study. Photoelectron spectroscopy has revealed that excitation of the alkali atoms via ...

2012

Proteolysis in microfluidic droplets: an approach to interface protein separation and peptide mass spectrometry

Hubert Girault, Liang Qiao

A versatile microreactor protocol based on microfluidic droplets has been developed for on-line protein digestion. Proteins separated by liquid chromatography are fractionated in water-in-oil droplets and digested in sequence. The microfluidic reactor acts ...

Royal Society of Chemistry2012

Electrochemical Push–Pull Scanner with Mass Spectrometry Detection

Hubert Girault, Andreas Stephan Lesch, Liang Qiao, Fernando Cortes Salazar, Dmitry Momotenko, Gunther Wittstock

This manuscript presents a push-pull electrochem. scanner able to image reactivity of initially dry surfaces by scanning electrochem. microscopy (SECM) and to probe mols. present or generated at the surface by mass spectrometry (MS). The proof-of-concept i ...

Amer Chemical Soc2012

On the utility of predictive chromatography to complement mass spectrometry based intact protein identification

Yury Tsybin, Hisham Ben Hamidane

The amino acid sequence determines the individual protein three-dimensional structure and its functioning in an organism. Therefore, "reading" a protein sequence and determining its changes due to mutations or post-translational modifications is one of the ...

Springer-Verlag2012

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Chromatographie en phase liquide-spectrométrie de masse

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

Desiccation shrinkage of non-clayey soils: a numerical study

On the Utility of Isotopic Fine Structure Mass Spectrometry in Protein Identification

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

In-Spray Supercharging of Peptides and Proteins in Electrospray Ionization Mass Spectrometry

Desorption of alkali atoms from 4He nanodroplets

Proteolysis in microfluidic droplets: an approach to interface protein separation and peptide mass spectrometry

Microchip Based Electrospray Mass Spectrometry for Investigation of Neurodegenerative Peptides

Electrochemical Push–Pull Scanner with Mass Spectrometry Detection

On the utility of predictive chromatography to complement mass spectrometry based intact protein identification

Graph Chatbot

Chattez avec Graph Search

Desorption of alkali atoms from 4He nanodroplets

On the Utility of Isotopic Fine Structure Mass Spectrometry in Protein Identification

Microchip Based Electrospray Mass Spectrometry for Investigation of Neurodegenerative Peptides

On the utility of predictive chromatography to complement mass spectrometry based intact protein identification

Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS

Proteolysis in microfluidic droplets: an approach to interface protein separation and peptide mass spectrometry

Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain

Desiccation shrinkage of non-clayey soils: a numerical study

Electrochemical Push–Pull Scanner with Mass Spectrometry Detection

In-Spray Supercharging of Peptides and Proteins in Electrospray Ionization Mass Spectrometry