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The zebrafish (Danio rerio) embryo toxicity test (DarT) is under consideration as an alternative to the acute fish toxicity test. Microscopically visible developmental disorders or death are the endpoints used to report on toxicity in DarT. These endpoints ...
In the mouse, over the last 20 years, a set of cell-surface markers and activities have been identified, enabling the isolation of bone marrow (BM) populations highly enriched in hematopoietic stem cells (HSCs). These HSCs have the ability to generate mult ...
Microarrays have become an important tool for studying the molecular basis of complex disease traits and fundamental biological processes. A common purpose of microarray experiments is the detection of genes that are differentially expressed under two cond ...
Inversion in Galois Fields is a famous primitive permutation for designing cryptographic algorithms e.g. for Rijndael because it has suitable differential and linear properties. Inputs and outputs are usually transformed by addition (e.g. XOR) to key bits. ...
Pathogenetic processes that facilitate the entry, replication, and persistence of Mycobacterium tuberculosis (MTB) in the mammalian host likely include the regulated expression of specific sets of genes at different stages of infection. Identification of g ...
Telomerase activation is crucial in human carcinogenesis. The limiting component of telomerase, the catalytic subunit (hTERT), is undetectable in normal somatic cells but present in most tumor cells, including the earliest stages of colon carcinoma. The me ...
A new lidar for the measurement of tropospheric ozone is proposed, based on the differential analysis of the Raman backscattered signals on nitrogen and oxygen, which is far less sensitive to the aerosols than the classical DIAL system. Using a third Raman ...
The effect of temperature on the Raman spectrum of Mg2SiO4-forsterite is investigated between 100 and 2000 K. The data, combined with those obtained at high pressure, are used to discuss the intrinsic anharmonicity of the Raman-active modes. Anharmonicity ...
This paper presents a regular layout fabric made of via-programmable MCML universal logic cells for structured ASIC applications and the associated design flow. The proposed structured ASIC fabric offers very high noise immunity due to the differential ope ...
A novel type of water-soluble prodrugs of cyclosporine A (CsA) is described, featuring a modular system of an enzyme-cleavable group, a solubilizing moiety and a chemodegradable spacer attached to the hydroxyl function of (4R)-4-[(E)-2-butenyl]-4-,N-dimeth ...
