Concept

Phospholipide

Publications associées (82)

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER

The endoplasmic reticulum (ER) is the site of maturation for secretory and membrane proteins in eukaryotic cells. Unsuccessful folding attempts are eventually interrupted and most folding-defective polypeptides are dislocated across the ER membrane and deg ...

2011

Formation and study of single metal ion–phospholipid complexes in biphasic electrospray ionization mass spectrometry

Hubert Girault, Daniel Filipe Dos Santos Alves Jana, Manuel Alejandro Méndez Agudelo, Michel Prudent

Single metal ion-phospholipid complexes are observed in biphasic electrospray ionization mass spectrometry (BESI-MS) using a dual-channel microsprayer. Such a microsprayer makes it possible to put into contact two immiscible liquids within the Taylor cone. ...

Royal Society of Chemistry2010

Molecular Simulation of the DMPC-Cholesterol Phase Diagram

Berend Smit

In this paper, we present a coarse-grained model of a hydrated saturated phospholipid bilayer (dimyristoylphosphatidylcholine, DMPC) containing cholesterol that we study using a hybrid dissipative particle dynamics-Monte Carlo method. This approach allows ...

2010

Characterization of supported lipid bilayers incorporating the phosphoinositides phosphatidylinositol 4,5-biphosphate and phosphoinositol-3,4,5-triphosphate by complementary techniques

Esther Amstad

Phosphoinositides are involved in a large number of processes in cells and it is very demanding to study individual protein-lipid interactions in vivo due to their rapid turnover and involvement in simultaneous events. Supported lipid bilayers (SLBs) conta ...

American Vacuum Society2010

Effect of cholesterol on the structure of a phospholipid bilayer

Berend Smit

Cholesterol plays an important role in regulating the properties of phospholipid membranes. To obtain a detailed understanding of the lipid‚Äìcholesterol interactions, we have developed a mesoscopic water‚Äìlipid‚Äìcholesterol model. In this model, we take ...

2009

Submicrometer tomography of cells by multiple-wavelength digital holographic microscopy in reflection

Christian Depeursinge, Tristan Colomb, Frédéric Montfort, Nicolas Pavillon, Benjamin Rappaz, Pierre Marquet, Jonas Kühn, Corinne Moratal

We present first results on a method enabling mechanical scanning-free tomography with submicrometer axial resolution by multiple-wavelength digital holographic microscopy. By sequentially acquiring reflection holograms and summing 20 wavefronts equally sp ...

2009

Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu

Knowledge of T-1 relaxation times can be important for accurate relative and absolute quantification of brain metabolites, for sensitivity optimizations, for characterizing molecular dynamics, and for studying changes induced by various pathological condit ...

Wiley-Blackwell2009

Peptide-Phospholipid Complex Formation at Liquid-Liquid Interfaces

Hubert Girault, Manuel Alejandro Méndez Agudelo, Michel Prudent, Bin Su

Two peptides known to interact with receptors embedded in cell membranes, angiotensin III (AngIII) and Leuenkephalin(LeuEnk), were studied electrochemically at the interface formed between two immiscible electrolyte solutions modified by an adsorbed monola ...

2008

The multiple roles of PtdIns(4)P - not just the precursor of PtdIns(4,5)P2

Giovanni D'Angelo

The phosphoinositides (PIs) are membrane phospholipids that actively operate at membrane-cytosol interfaces through the recruitment of a number of effector proteins. In this context, each of the seven different PI species represents a topological determina ...

2008

Evf, a virulence factor produced by the Drosophila pathogen Erwinia carotovora, is an S-palmitoylated protein with a new fold that binds to lipid vesicles

Bruno Lemaitre

Erwinia carotovora are phytopathogenic Gram-negative bacteria of agronomic interest as these bacteria are responsible for fruit soft rot and use insects as dissemination vectors. The Erwinia carotovora carotovora strain 15 (Ecc15) is capable of persisting ...

2008

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search