Ethnomedicine is a study or comparison of the traditional medicine based on bioactive compounds in plants and animals and practiced by various ethnic groups, especially those with little access to western medicines, e.g., indigenous peoples. The word ethnomedicine is sometimes used as a synonym for traditional medicine.
Ethnomedical research is interdisciplinary; in its study of traditional medicines, it applies the methods of ethnobotany and medical anthropology. Often, the medicine traditions it studies are preserved only by oral tradition. In addition to plants, some of these traditions constitute significant interactions with insects on the Indian Subcontinent, in Africa, or elsewhere around the globe.
Scientific ethnomedical studies constitute either anthropological research or drug discovery research. Anthropological studies examine the cultural perception and context of a traditional medicine. Ethnomedicine has been used as a starting point in drug discovery, specifically those using reverse pharmacological techniques.
Ethnopharmacology is a related field which studies ethnic groups and their use of plant compounds. It is linked to pharmacognosy, phytotherapy (study of medicinal plants) use and ethnobotany, as this is a source of lead compounds for drug discovery. Emphasis has long been on traditional medicines, although the approach also has proven useful to the study of modern pharmaceuticals.
It involves studies of the:
identification and ethnotaxonomy (cognitive categorisation) of the (eventual) natural material, from which the candidate compound will be produced
traditional preparation of the pharmaceutical forms
bio-evaluation of the possible pharmacological action of such preparations (ethnopharmacology)
their potential for clinical effectiveness
socio-medical aspects implied in the uses of these compounds (medical anthropology).
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The use of medicinal plants as a therapy alternative is old as human existence itself. Nowadays, the search for effective molecules for chronic diseases treatments has increased. The cardiometabolic disorders still the main cause of death worldwide and pla ...
Traditional knowledge (TK), indigenous knowledge (IK) and local knowledge generally refer to knowledge systems embedded in the cultural traditions of regional, indigenous, or local communities. According to the World Intellectual Property Organization (WIPO) and the United Nations (UN), traditional knowledge and traditional cultural expressions (TCE) are both types of indigenous knowledge. Traditional knowledge includes types of knowledge about traditional technologies of subsistence (e.g.
L'ethnobotanique, contraction d'ethnologie et de botanique, est l'étude des relations entre l'Homme et les plantes. Son domaine d'étude implique une large gamme de disciplines depuis les recherches archéologiques sur les civilisations anciennes jusqu'à la bio-ingénierie de nouvelles cultures comme le blé. La méthode ethnobotanique part de la connaissance empirique acquise au cours de centaines de générations, basée sur les observations de masse (méthode des essais et erreurs) et généralement sur une tradition orale, et conservée grâce à la mémoire collective de groupes sociaux.
A lead compound (ˈliːd, i.e. a "leading" compound, not to be confused with various compounds of the metallic element lead) in drug discovery is a chemical compound that has pharmacological or biological activity likely to be therapeutically useful, but may nevertheless have suboptimal structure that requires modification to fit better to the target; lead drugs offer the prospect of being followed by back-up compounds. Its chemical structure serves as a starting point for chemical modifications in order to improve potency, selectivity, or pharmacokinetic parameters.