R-410A, sold under the trademarked names AZ-20, EcoFluor R410, Forane 410A, Genetron R410A, Puron, and Suva 410A, is a zeotropic but near-azeotropic mixture of difluoromethane (CH2F2, called R-32) and pentafluoroethane (CHF2CF3, called R-125) that is used as a refrigerant in air conditioning and heat pump applications. R-410A cylinders were colored rose but are no longer specially color-coded, now bearing a standard light gray color.
On December 27, 2020, the United States Congress passed the American Innovation and Manufacturing (AIM) Act, which directs US Environmental Protection Agency (EPA) to phase down production and consumption of hydrofluorocarbons (HFCs). HFCs have a high global warming potential and contribute to climate change. Rules developed under the AIM Act require HFC production and consumption to be reduced by 85% from 2022 to 2036. R-410A will be restricted by this Act because it contains the HFC R-125. Other refrigerants (like R-32 and R-454B) will replace R-410A in most applications, just as R-410A replaced the earlier refrigerant, R-22.
R-410A was invented and patented by Allied Signal (now Honeywell) in 1991. Other producers around the world have been licensed to manufacture and sell R-410A, but Honeywell continues to be the leader in capacity and sales. R-410A was successfully commercialized in the air conditioning segment by a combined effort of Carrier Corporation, Emerson Climate Technologies, Inc., Copeland Scroll Compressors (a division of Emerson Electric Company), and Allied Signal. Carrier Corporation was the first company to introduce an R-410A-based residential air conditioning unit into the market in 1996 and holds the trademark "Puron".
R-410A replaced R-22 as the preferred refrigerant for use in residential and commercial air conditioners in Japan, Europe, and the United States.
Parts designed specifically for R-410A must be used, as R-410A operates at higher pressures than other refrigerants. R-410A systems thus require service personnel to use different tools, equipment, safety standards, and techniques.