Concept

Projet de séquençage de génome

Publications associées (330)

Hydrocontest: Computational Fluid Dynamics of hydrofoils

This project is developed within the scope of HydroContest which is an inter-school competition for the design of a racing boat with a high focus on energetic efficiency; the goal is to maximize the speed of the boat under the constraint of a limited power ...

2014

The Chills and Thrills of Whole Genome Sequencing

Jean-Pierre Hubaux, Erman Ayday

In recent years, whole genome sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a wide range of revol ...

2013

Genome analysis of Desulfotomaculum kuznetsovii reveals a physiological similarity with Pelotomaculum thermopropionicum

Rizlan Bernier-Latmani

Desulfotomaculum kuznetsovii is a moderately thermophilic member of the polyphyletic spore-forming genus Desulfotomaculum in the family Peptococcaceae. This species is of interest because it originates from deep subsurface thermal mineral water at a depth ...

Genomic Stand Consort2013

The Janthinobacterium sp. HH01 Genome Encodes a Homologue of the V. cholerae CqsA and L. pneumophila LqsA Autoinducer Synthases

Melanie Blokesch

Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established. The genome ...

Public Library of Science2013

Updating and curating metabolic pathways of TB

Jocelyne Lew

The sequencing of complete genomes has accelerated biomedical research by providing information about the overall coding capacity of bacterial chromosomes. The original TB annotation resulted in putative functional assignment of similar to 60% of the genes ...

Churchill Livingstone2013

Addressing the Concerns of the Lacks Family: Quantification of Kin Genomic Privacy

Jean-Pierre Hubaux, Mathias Jacques Jean-Marc Humbert, Amalio Telenti, Erman Ayday

The rapid progress in human-genome sequencing is leading to a high availability of genomic data. This data is notoriously very sensitive and stable in time. It is also highly correlated among relatives. A growing number of genomes are becoming accessible o ...

2013

Thermodynamics-Based Significance Ranking of Candidates for Metabolomics

Vassily Hatzimanikatis

Cellular metabolism is the driving force of all living cells and organisms. Numerous research projects undertaken over the past century have attempted to decipher the function and operating principles of metabolism with varying degrees of success. A wide s ...

2013

Privacy-Enhancing Technologies for Medical Tests Using Genomic Data

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro

We propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients’ genomic data. Focusing specifically on a typical disease-susceptibility test, we develop a new architecture (between the patient and the ...

2013

European genetic diversity and susceptibility to pathogens

Jacques Fellay, Amalio Telenti

Infectious diseases, both in their endemic and epidemic forms, have shaped the human genome. Ecology has also contributed to geographically constrained pressures on human populations. There are now multiple examples of population-specific genetic variants ...

2013

Personal Use of the Genomic Data: Privacy vs. Storage Cost

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro

In this paper, we propose privacy-enhancing technologies for personal use of the genomic data and analyze the tradeoff between genomic privacy and storage cost of the genomes. First, we highlight the potential privacy threats on the genomic data. Then, foc ...

2013

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