Concept
Membrane mitochondriale interne
Publications associées (76)
Glutamate transport decreases mitochondrial pH and modulates oxidative metabolism in astrocytes
Hélène Danielle Perreten Lambert, Sylvain Eric Lengacher, Jean-Yves Chatton
During synaptic activity, the clearance of neuronally released glutamate leads to an intracellular sodium concentration increase in astrocytes that is associated with significant metabolic cost. The proximity of mitochondria at glutamate uptake sites in as ...
2011Lentiviral Transgenesis as a Tool to Study the Role of Uncoupling Protein Isoforms in the Nervous System
Hélène Danielle Perreten Lambert
A tight coupling exists between synaptic activity and glucose utilization by astrocytes. Metabolic cooperation between neurons and astrocytes mediates this coupling. During synaptic activation, glutamate that is released in the synaptic cleft as a neurotra ...
EPFL2011Cytotoxic Property of Surfactant-Cobalt(III) Complexes on a Human Breast Cancer Cell Line
The cancer chemotherapeutic potential of surfactant-cobalt(III) complexes, cis-Co(bpy)(2)(C14H29NH2)Cl(2) center dot 3 H2O (1) and cis-Co(phen)(2)(C14H29NH2)Cl(2) center dot 3 H2O (2) (bpy 2,2 '-bipyridine, phen 1,10-phenanthroline) on MCF- ...
2011Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion
Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively. Fzo1/Mfns possess two medial transmembrane domains, which pl ...
Rockefeller University Press2009Mitochondrial bovine ADP/ATP carrier in detergent is predominantly monomeric but also forms multimeric species
ADP/ATP carriers (AACs) are major and essential constituents of the inner mitochondrial membrane. They drive the import of ADP and the export of newly synthesized ATP. They were described as functional dimers from the 1980s until the structures of the AAC ...
American Chemical Society2008Mini review on the structure and supramolecular assembly of VDAC
The Voltage Dependent Anion Channel (VDAC) is the most abundant protein in the outer membrane of mitochondria. This strategic localization puts it at the heart of a great number of phenomena. Its recent implication in apoptosis is an example of the major i ...
2008