Concept
Fumarase
Publications associées (4)
Mitochondrial unfolded protein response, its molecular mechanism and physiological impact
Mitochondria are the main producers of ATP, the energy currency of the cell, and they perform a wide array of other fundamental functions. These organelles are essential not only for cellular metabolism, but also for organismal physiology and lifespan. A r ...
EPFL2016Production of a thermostable fumarase in Saccharomyces cerevisiae for the bioconversion of fumarate to L-malate
The gene encoding fumarase (fum) from Thermus thermophilus was expressed in yeast Saccharomyces cerevisiae. The recombinant cells were heated at 70°C to inactivate indigenous enzymes and used for the bioconversion of fumaric acid to L-malic acid. By heatin ...
2011The role of contact sites between inner and outer mitochondrial membrane in energy transfer
Three functions have been suggested to be localized in contact sites between the inner and the outer membrane of mitochondria from mammalian cells: (i) transfer of energy from matrix to cytosol through the action of peripheral kinases; (ii) import of mitoc ...
1990