Concept

Neuromodulation (medicine)

Publications associées (124)

Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury

Silvestro Micera, Grégoire Courtine, Marco Bonizzato, Polina Shkorbatova, Natalia Pavlova, Galyna Pidpruzhnykova

The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment recovery from neurological disorders. To test this hypothesis, we conceived a brain-controlled neuromodulation therapy that combines the technical and practi ...

Nature Publishing Group2018

A sensory information compliant spinal cord stimulation system for the rehabilitation of motor functions

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Emanuele Formento, Karen Minassian

The present invention refers to a system for stimulation of the spinal cord for the rehabilitation of motor function in subjects with spinal cord injury or other motor disorders. Said system comprises a programmable implantable pulse generator (IPG), opera ...

2018

Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities

Friedhelm Christoph Hummel, Estelle Emeline Raffin

More than 1.5 million people suffer a stroke in Europe per year and more than 70% of stroke survivors experience limited functional recovery of their upper limb, resulting in diminished quality of life. Therefore, interventions to address upper-limb impair ...

2018

Closed-Loop Functional Electrical Stimulation for Gait Training for Patients with Paraplegia

Mohamed Bouri, Solaiman Shokur

This paper presents a novel functional electrical stimulation paradigm to generate locomotion in paraplegic patients. We propose a closed-loop surface functional electrical stimulation (sFES) of 16 lower-limb muscles to produce all subphases of the gait. T ...

IEEE2018

Brain-actuated functional electrical stimulation elicits lasting arm motor recovery after stroke

José del Rocio Millán Ruiz, Hua Zhang, Robert Leeb, Inaki Asier Iturrate Gil, Serafeim Perdikis, Andrea Biasiucci, Tiffany Corbet, Thomas Schmidlin, Dragana Viceic

Brain-computer interfaces (BCI) are used in stroke rehabilitation to translate brain signals into intended movements of the paralyzed limb. However, the efficacy and mechanisms of BCI-based therapies remain unclear. Here we show that BCI coupled to functio ...

2018

Long-term functionality of a soft electrode array for epidural spinal cord stimulation in a minipig model

Stéphanie Lacour, Grégoire Courtine, Jocelyne Bloch, Marco Capogrosso, Nicolas Vachicouras, Giuseppe Schiavone, Fabien Bertrand Paul Wagner, Florian Dylan Fallegger, Beatrice Barra, Xiaoyang Kang

Long-term biointegration of man-made neural interfaces is influenced by the mechanical properties of the implant materials. Substantial experimental work currently aims at replacing conventional hard implant materials with soft alternatives that can favour ...

IEEE2018

A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Stéphanie Lacour, Diego Ghezzi, Sandra Gribi, Sophie du Bois de Dunilac

Peripheral nerves are anisotropic and heterogeneous neural tissues. Their complex physiology restricts realistic in vitro models, and high resolution and selective probing of axonal activity. Here, we present a nerve-on-a-chip platform that enables rapid e ...

2018

Electronic dura mater soft, multimodal neural interfaces

Arthur Edouard Hirsch

Neuroprosthetic devices are engineered to study, support or replace impaired functions of the nervous system. The neural interface is an essential element of neuroprosthetic systems as it allows for transduction of signals and stimuli of desired functions ...

EPFL2018

Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Laurijn Rianne Draaisma

Stroke is a main cause for long-term disability. Stroke symptoms cover various domains, e.g., motor, sensory, language, or other cognitive functions. In clinical practice and rehabilitation research, especially motor impairment attracts much attention. How ...

2018

Prosthetic Control and Sensory Feedback for Upper Limb Amputees

Huaiqi Huang

Hand amputation could dramatically degrade the life quality of amputees. Many amputees use prostheses to restore part of the hand functions. Myoelectric prosthesis provides the most dexterous control. However, they are facing high rejection rate. One of th ...

EPFL2018

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