Publications associées à Multiple sequence alignment

Quantitative characterization of the inorganic phosphate gene regulatory networks in S. cerevisiae and bottom up engineering an orthogonal gene network

Gene regulatory networks (GRNs) play a crucial role in an organism's response to changing environmental conditions. Cellular behaviors typically result from the integration of multiple gene outputs, and their regulation often demands precise control of num ...

EPFL2024

TTool: A Supervised Artificial Intelligence-Assisted Visual Pose Detector for Tool Heads in Augmented Reality Woodworking

Yves Weinand, Andrea Settimi, Julien Gamerro, Florian Aymanns, Naravich Chutisilp

We present TimberTool (TTool v2.1.1), a software designed for woodworking tasks assisted by augmented reality (AR), emphasizing its essential function of the real-time localization of a tool head’s poses within camera frames. The localization process, a fu ...

2024

Generative power of a protein language model trained on multiple sequence alignments

Anne-Florence Raphaëlle Bitbol, Umberto Lupo, Damiano Sgarbossa

Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function. They thus open the possibility for generating no ...

eLIFE SCIENCES PUBL LTD2023

Combining phylogeny and coevolution improves the inference of interaction partners among paralogous proteins

Anne-Florence Raphaëlle Bitbol

Author summaryWhen two protein families interact, their sequences feature statistical dependencies. First, interacting proteins tend to share a common evolutionary history. Second, maintaining structure and interactions through the course of evolution yiel ...

PUBLIC LIBRARY SCIENCE2023

Impact of phylogeny on structural contact inference from protein sequence data

Anne-Florence Raphaëlle Bitbol, Umberto Lupo, Nicola Dietler

Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins. They rely on correlations in amino acid usage at contacting sites. Because homologous proteins share a common ance ...

ROYAL SOC2023

Smart filter aided domain adversarial neural network for fault diagnosis in noisy industrial scenarios

Olga Fink, Gaëtan Michel Frusque, Tianfu Li, Qi Li, Baorui Dai

The application of unsupervised domain adaptation (UDA)-based fault diagnosis methods has shown significant efficacy in industrial settings, facilitating the transfer of operational experience and fault signatures between different operating conditions, di ...

2023

Species-specific regulation of XIST by the JPX/FTX orthologs

Olga Marie Louise Rosspopoff

X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolved concom ...

OXFORD UNIV PRESS2023

Learnable Wavelet Transform and Domain Adversarial Learning for Enhanced Bearing Fault Diagnosis

Olga Fink, Gaëtan Michel Frusque, Qi Li, Baorui Dai

The application of unsupervised domain adaptation (UDA)-based fault diagnosis methods has shown significant efficacy in industrial settings, facilitating the transfer of operational experience and fault signatures between different operating conditions, di ...

Research Publishing2023

Robust Outlier Rejection for 3D Registration with Variational Bayes

Mathieu Salzmann, Zheng Dang, Jiancheng Yang, Zhen Wei, Haobo Jiang

Learning-based outlier (mismatched correspondence) rejection for robust 3D registration generally formulates the outlier removal as an inlier/outlier classification problem. The core for this to be successful is to learn the discriminative inlier/outlier f ...

Ieee Computer Soc2023

fGOT: Graph Distances Based on Filters and Optimal Transport

Pascal Frossard, Mireille El Gheche, Hermina Petric Maretic, Giovanni Chierchia

Graph comparison deals with identifying similarities and dissimilarities between graphs. A major obstacle is the unknown alignment of graphs, as well as the lack of accurate and inexpensive comparison metrics. In this work we introduce the filter graph dis ...

ASSOC ADVANCEMENT ARTIFICIAL INTELLIGENCE2022