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Background and objective: To automatically identify patients with diabetes mellitus (DM) who have high risk of developing diabetic foot, via an unsupervised machine learning technique. Methods: We collected a new database containing 54 known risk factors f ...
2020
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Hypoglycemia is critical condition during diabetic treatment that involves intensive insulin therapy, and it may impair brain function. We aimed to compare cortical responses of three hypoglycemic phases and the restoration of glycemia to control levels af ...
Regenerative medicine aims to repair body tissues when natural mechanisms fail. Growth factors (GFs) are essential proteins that promote tissue regeneration upon injury, and as such, are very promising therapeutic drugs in regenerative medicine. Due to the ...
This thesis has been put in place during the development of an innovative medical device which consists in an intelligent footwear for foot plantar pressure redistribution in diabetic patients. In fact, despite the several sophisticated techniques develope ...
The invention relates to a system for adjusting pressure locally acting on the skin. Said system includes a set of adjacent modules distributed so as to form a layer. Each module includes a cushion capable of changing shape and comprising a cavity, a valve ...
2017
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This paper is focused on modeling and performance investigation of insulin injection pens used by diabetic persons. A smart pen cap with two electrodes is used as a capacitive sensor for insulin dose detection and is presented in details. To faithfully ana ...
IEEE2019
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Lymphangiogenesis occurs in inflammation and wound healing, yet its functional roles in these processes are not fully understood. Consequently, clinically relevant strategies for therapeutic lymphangiogenesis remain underdeveloped, particularly using growt ...
2017
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In the proposed work, the dynamic performances of a miniature soft Magneto-Rheological (MR) shock absorber are analyzed. The final application for which the damper has been designed and in which it will be embedded is a variable stiffness insole for patien ...
Institute of Electrical and Electronics Engineers Inc.2016
Diabetic foot ulcerations (DFUs) represent a major medical, social, and economic problem. Therapeutic options are restricted due to a poor understanding of the pathogenic mechanisms. The Notch pathway plays a pivotal role in cell differentiation, prolifera ...
Brain glucose hypometabolism has been singled out as an important contributor and possibly main trigger to Alzheimer's disease (AD). Intracerebroventricular injections of streptozotocin (icv-STZ) cause brain glucose hypometabolism without systemic diabetes ...