Concept

Clinical research

Publications associées (283)

The wheelchair as a full-body tool extending the peripersonal space

Olaf Blanke, Andrea Serino, Jean-Paul Noel, Elisa Canzoneri

Dedicated multisensory mechanisms in the brain represent peripersonal space (PPS), a limited portion of space immediately surrounding the body. Previous studies have illustrated the malleability of PPS representation through hand-object interaction, showin ...

Frontiers Research Foundation2015

Towards non-invasive hybrid brain-computer interfaces: Framework, practice, clinical application and beyond

José del Rocio Millán Ruiz, Robert Leeb

In their early days, BCIs were only considered as control channel for end users with severe motor impairments such as people in the locked-in state. But, thanks to the multidisciplinary progress achieved over the last decade, the range of BCI applications ...

Ieee-Inst Electrical Electronics Engineers Inc2015

Mathematical Modeling in Full-Field Optical Coherence Elastography

Pierre Robert Maurice Millien

We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, realtime processing, and noninvasive imaging. We develop a novel algorithm for trans ...

Society for Industrial and Applied Mathematics2015

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions

Yury Tsybin

Hemoglobin disorder diagnosis is a complex procedure combining several analytical steps. Due to the lack of specificity of the currently used protein analysis methods, the identification of uncommon hemoglobin variants (proteoforms) can become a hard task ...

Springer Heidelberg2015

A Cloud-Based eHealth Architecture for Privacy Preserving Data Integration

Karl Aberer, Michael Ignaz Schumacher, Matteo Vasirani, Alevtina Dubovitskaya

In this paper, we address the problem of building an anonymized medical database from multiple sources. Our proposed solution defines how to achieve data integration in a heterogeneous network of many clinical institutions, while preserving data utility an ...

Springer International Publishing2015

Photothermal cellular stimulation in functional bio-polymer interfaces

Diego Ghezzi

Hybrid interfaces between organic semiconductors and living tissues represent a new tool for in-vitro and in-vivo applications, bearing a huge potential, from basic researches to clinical applications. In particular, light sensitive conjugated polymers can ...

2015

Engineering antigen-specific immunological tolerance

Stephane Kontos, Jeffrey Alan Hubbell, Alizée Jéléna Grimm

Unwanted immunity develops in response to many protein drugs, in autoimmunity, in allergy, and in transplantation. Approaches to induce immunological tolerance aim to either prevent these responses or reverse them after they have already taken place. We pr ...

Current Biology Ltd2015

Wireless Neurosensor for Full-Spectrum Electrophysiology Recordings during Free Behavior

Grégoire Courtine, Hao Li, David Allenson Borton, Yao Lu, Jean François Pierre Laurens

Brain recordings in large animal models and humans typically rely on a tethered connection, which has restricted the spectrum of accessible experimental and clinical applications. To overcome this limitation, we have engineered a compact, lightweight, high ...

Cell Press2014

Label-free Analytics by Transmission Localized-SPR and its Application to Small Molecules Monitoring in Serum

Giulia Cappi

In the frame of therapeutic drug monitoring and personalized medicine, point-of-care systems (POCs) that can help overcome long waiting times for results and costly procedures of clinical tests are highly desirable. At present, the detection of low-molecul ...

EPFL2014

Development of a Database for Translational Spinal Cord Injury Research

Grégoire Courtine

Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of ...

Mary Ann Liebert2014

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