Concept

Hormèse

Publications associées (13)

Delayed gamma fraction determination in the zero power reactor CROCUS

Andreas Pautz, Vincent Pierre Lamirand, Oskari Ville Pakari, Pavel Frajtag, Tom Mager

Gamma rays are an inextricable part of a nuclear reactor's radiation field, and as such require characterization for dose rate estimations required for the radiation protection of personnel, material choices, and the design of nuclear facilities. Most comm ...

EDP SCIENCES S A2021

Grayscale e-beam lithography: Effects of a delayed development for well-controlled 3D patterning

Henning Paul-Julius Stahlberg

Grayscale electron beam lithography (g-EBL) is a fabrication technique that allows for tunable control of resist topography. In most cases, the height of the structures is in the submicron regime. Here, we present an extensive experimental characterization ...

2020

Influence of Halo Implantations on the Total Ionizing Dose Response of 28-nm pMOSFETs Irradiated to Ultrahigh Doses

Christian Enz

In this paper, the total ionizing dose (TID) response of a commercial 28-nm high-k CMOS technology at ultrahigh doses is measured and discussed. The degradation of pMOSFETs depends not only on the channel width but also on the channel length. Short-channel ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2019

Highly sensitive enzymatic MWCNTs-based biosensors for detection of abiraterone in human serum

Giovanni De Micheli, Sandro Carrara, Nima Aliakbarinodehi

A highly-sensitive enzymatic biosensor is successfully experimented for detection of abiraterone in human serum with significance in personalized medicine and point-of-care chemotherapy of patients with metastatic prostate cancer. The dynamic range and lim ...

2018

Aptamer-based Field-Effect Biosensor for Tenofovir Detection

Giovanni De Micheli, Sandro Carrara

During medical treatment it is critical to maintain the circulatory concentration of drugs within their therapeutic range. A novel biosensor is presented in this work to address the lack of a reliable point-of-care drug monitoring system in the market. The ...

2017

Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis

Rolf Gruetter, Lijing Xin, Kim Do, Benoît Schaller, Huanxiang Lu

BACKGROUND: Oxidative stress and glutathione (GSH) metabolism dysregulation has been implicated in the pathophysiology of schizophrenia. GAG-trinucleotide repeat (TNR) polymorphisms in the glutamate-cysteine ligase catalytic gene (GCLC), the rate-limiting ...

Oxford University Press2016

A Control Flow Prototype for a Dose Recommending Device for Chronic Myeloid Leukemia Patients

Giovanni De Micheli, Alena Simalatsar, Wenqi You Dubout, Dechao Sun

In this paper we present a prototype of a control flow for an a posteriori drug dose adaptation for Chronic Myelogenous Leukemia (CML) patients. The control flow is modeled using Timed Automata extended with Tasks (TAT) model. The feedback loop of the cont ...

2013

In vivo real-time metabolic studies in mice at physiological concentrations following 1-13C lactate injection

Rolf Gruetter, Mor-Miri Mishkovsky, Tian Cheng, Arnaud Comment, Yuhei Takado

The real-time metabolic transformation of lactate in the mouse head was monitored following the injection of hyperpolarized 1-13C lactate at physiological doses. The results were compared with metabolic studies performed with hyperpolarized 1-13C pyruvate ...

2012

Développement et validation de méthodes dosimétriques en ligne pour le traitement du cancer de la prostate

Currently, the treatment of prostate cancer under open MRI at the University of Geneva Hospital, applying high dose rate (HDR) brachytherapy, involves three main steps : needle implantation, dosimetric calculations and irradiation. As such, there is no pre ...

EPFL2005

Interstitial photodynamic therapy with tetra(m-hydroxyphenyl)chlorin: tumor versus striated muscle damage

Hubert van den Bergh, Georges Wagnières, Alain Woodtli

Purpose: The present study was initiated to det. the conditions under which a single photodynamic treatment would induce maximal damage to a tumor with no or at least minimal reversible damage to a normal striated muscle. Methods and Materials: The techniq ...

1998

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