Publications associées à Cell damage

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

Joachim Lingner, Antonio Porro, Sascha Feuerhahn

Telomeres protect chromosome ends from being recognized as sites of DNA damage. Upon telomere shortening or telomere uncapping induced by loss of telomeric repeat-binding factor 2 (TRF2), telomeres elicit a DNA-damage response leading to cellular senescenc ...

Elsevier2014

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

Yi Zhang, Friedrich Beermann, Jie Zhang, Yuan Liu, Qian Zhang, Li Li, Ang Li, Ping Chen, Bo Zhou, Rong Wu

Autophagy is linked to cell death, yet the associated mechanisms are largely undercharacterized. We discovered that melanoma, which is generally resistant to drug-induced apoptosis, can undergo autophagic cell death with the participation of orphan nuclear ...

Nature Publishing Group2014

Functional characterization of the TERRA transcriptome at damaged telomeres

Joachim Lingner, Jacques Rougemont, Antonio Porro, Julien Delafontaine, Sascha Feuerhahn

Telomere deprotection occurs during tumorigenesis and aging upon telomere shortening or loss of the telomeric shelterin component TRF2. Deprotected telomeres undergo changes in chromatin structure and elicit a DNA damage response (DDR) that leads to cellul ...

Nature Publishing Group2014

Considerations when investigating IncRNA function in vivo

Denis Duboule

Although a small number of the vast array of animal long non-coding RNAs (IncRNAs) have known effects on cellular processes examined in vitro, the extent of their contributions to normal cell processes throughout development, differentiation and disease fo ...

Elife Sciences Publications Ltd2014

Subtle differences in virus composition affect disinfection kinetics and mechanisms

Tamar Kohn, Krista Rule Wigginton, Brian Pecson, Michele Cascella, Anne Thérèse Sigstam

Viral disinfection kinetics have been studied in depth, but the molecular-level inactivation mechanisms are not understood. Consequently, it is difficult to predict the disinfection behavior of non-culturable viruses, even when related, culturable viruses ...

American Society for Microbiology2013

Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein

Matteo Di Piazza

Clinical approaches for tumor treatment often rely on combination therapy where a DNA damaging agent is used in combination with a DNA repair protein inhibitor. For this reason, great efforts have been made during the last decade to identify inhibitors of ...

Biotechniques Office2013

Imaging cells and sub-cellular structures with ultrahigh resolution full-field X-ray microscopy

Giorgio Margaritondo, Chao Wang, Yong Yang

Our experimental results demonstrate that full-field hard-X-ray microscopy is finally able to investigate the internal structure of cells in tissues. This result was made possible by three main factors: the use of a coherent (synchrotron) source of X-rays, ...

Pergamon-Elsevier Science Ltd2013

Combined use of transcranial magnetic stimulation and metal electrode implants: a theoretical assessment of safety considerations

Juan Ramon Mosig, Hossein Rouhani, Laleh Golestanirad, Kamal Shahim

This paper provides a theoretical assessment of the safety considerations encountered in the simultaneous use of transcranial magnetic stimulation (TMS) and neurological interventions involving implanted metallic electrodes, such as electrocorticography. M ...

Institute of Physics2012

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Cell damage

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

Functional characterization of the TERRA transcriptome at damaged telomeres

Considerations when investigating IncRNA function in vivo

Subtle differences in virus composition affect disinfection kinetics and mechanisms

The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine

Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein

Imaging cells and sub-cellular structures with ultrahigh resolution full-field X-ray microscopy

Combined use of transcranial magnetic stimulation and metal electrode implants: a theoretical assessment of safety considerations

Graph Chatbot

Chattez avec Graph Search

Subtle differences in virus composition affect disinfection kinetics and mechanisms

The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine

Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein

Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

Functional characterization of the TERRA transcriptome at damaged telomeres

Considerations when investigating IncRNA function in vivo

Imaging cells and sub-cellular structures with ultrahigh resolution full-field X-ray microscopy

TERRA-Reinforced Association of LSD1 with MRE11 Promotes Processing of Uncapped Telomeres

Combined use of transcranial magnetic stimulation and metal electrode implants: a theoretical assessment of safety considerations

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway