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Genome-scale metabolic reconstructions (GEMs) are valuable resources for understanding and redesigning cellular networks as they encapsulate all the known biochemistry of the organisms from genes to proteins to their functions. Complexity of these large me ...
CONSPECTUS: Atomic crystals of two-dimensional materials consisting of single sheets extracted from layered materials are gaining increasing attention. The most well-known material from this group is graphene, a single layer of graphite that can be extract ...
The hundredth anniversary of Robert Barany's Nobel Prize in Medicine offers the opportunity to highlight the importance of his discoveries on the physiology and pathophysiology of the vestibular organs. Barany developed the method of caloric vestibular sti ...
The immense diversity of microbial life found in the vadose zone reflects the extremely heterogeneous and highly dynamic aquatic and chemical environments formed within soil pore spaces. The notion of planktonian free swimming microbes is unrealistic under ...
Sirtuins (Sirts) compose a family of NAD(+)-dependent deacetylases and/or ADP-ribosyltransferases, which have been implicated in aging, metabolism, and tolerance to oxidative stress. Many of the biological processes regulated by Sirts result from the adapt ...
Using Monte Carlo simulations for a semi-infinite medium representing a skeletal muscle tissue, it is demonstrated that the zero- and first-order moments of the power spectrum for a representative pixel of a full-field laser-Doppler imager behave different ...
Cell-intrinsic checkpoints limit the proliferative capacity of primary cells in response to telomere dysfunction. It is not known, however, whether telomere dysfunction contributes to cell-extrinsic alterations that impair stem cell function and organ home ...
The peroxisome proliferator activated receptor gamma (PPARgamma) is a member in the nuclear receptor superfamily which mediates part of the regulatory effects of dietary fatty acids on gene expression. As PPARgamma also coordinates adipocyte differentiatio ...
In 2003, the Nobel Assembly at the Karolinska Institute has awarded the Nobel Prize in Medicine or Physiology to Paul Lauterbur and Peter Mansfield for their seminal discoveries concerning the development of Magnetic Resonance Imaging (MRI), a non-invasive ...
Lattices abound in nature—from the crystal structure of minerals to the honey-comb organization of ommatidia in the compound eye of insects. These arrangements provide solutions for optimal packings, efficient resource distribution, and cryptographic proto ...