Concept

Biologie évolutive du développement

Publications associées (188)

Morphological Evolution of Physical Robots through Model-Free Phenotype Development

Artificial evolution of physical systems is a stochastic optimization method in which physical machines are iteratively adapted to a target function. The key for a meaningful design optimization is the capability to build variations of physical machines th ...

2015

Scaling Characteristics of Rill Networks

David Andrew Barry, Seifeddine Jomaa, Mohsen Cheraghi

Sediment transport in overland flow interacts dynamically with the soil surface morphology, which is often assumed to be static. This assumption, although it limits the predictive capacity of models, is reasonable since the morphological evolution is diffi ...

2015

Large-Scale Conformational Transitions and Dimerization Are Encoded in the Amino-Acid Sequences of Hsp70 Chaperones

Paolo De Los Rios, Alessandro Barducci, Duccio Malinverni

Hsp70s are a class of ubiquitous and highly conserved molecular chaperones playing a central role in the regulation of proteostasis in the cell. Hsp70s assist a myriad of cellular processes by binding unfolded or misfolded substrates during a complex bioch ...

Public Library Science2015

Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856

Tobias Johannes Schmid, Roel Paulus Josephus Bevers

The Hawaiian strain (CB4856) of Caenorhabditis elegans is one of the most divergent from the canonical laboratory strain N2 and has been widely used in developmental, population, and evolutionary studies. To enhance the utility of the strain, we have gener ...

2015

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model

Denis Duboule

The tetrapod vertebral column has become increasingly complex during evolution as an adaptation to a terrestrial life. At the same time, the evolution of the vertebral formula became subject to developmental constraints acting on the size of the cervical a ...

Elsevier2015

Contribution of recombination to the evolutionary history of HIV

Séverine Vuilleumier Varisco

Purpose of review: An improved understanding of how recombination affects the evolutionary history of HIV is crucial to understand its current and future evolution. The present review aims to disentangle the manifold effects of recombination on HIV by disc ...

2015

Big answers from small worlds: a user's guide for protist microcosms as a model system in ecology and evolution

Andrea Giometto, Florian Altermatt

Laboratory microcosm experiments using protists as model organisms have a long tradition and are widely used to investigate general concepts in population biology, community ecology and evolutionary biology. Many variables of interest are measured in order ...

Wiley-Blackwell2015

From Embryo to Adult: Hematopoiesis along the Drosophila Life Cycle

Bruno Lemaitre, Elodie Julie Virginie Ramond

Studies on Drosophila hematopoiesis have thus far focused on the embryonic and larval origin of hemocytes, the fly blood cells. In this issue of Developmental Cell, Ghosh et al. (2015) identify adult hematopoietic hubs containing progenitors that can diffe ...

Cell Press2015

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

Denis Duboule, Fabrice Daniel Darbellay, Nicolas Lonfat

Hox genes are required during the morphogenesis of both vertebrate digits and external genitals. We investigated whether transcription in such distinct contexts involves a shared enhancer-containing landscape. We show that the same regulatory topology is u ...

Amer Assoc Advancement Science2014

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

Denis Duboule, Guillaume Andrey, Dagmar Iber, Jing Liu

The large spectrum of limb morphologies reflects the wide evolutionary diversification of the basic pentadactyl pattern in tetrapods. In even-toed ungulates (artiodactyls, including cattle), limbs are adapted for running as a consequence of progressive red ...

Nature Publishing Group2014

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