Concept
Dynéine
Publications associées (55)
Method and system for determining intracellular mediators' activity
Philippe Renaud, Horst Vogel, Thamani Dahoun, Margaux Catherine Marie Duchamp
A method for determining the presence of a molecule coupled to the cytoplasmic side of a cellular membrane is disclosed. The method is implemented in a microfluidic setting and is particularly suitable for determining the presence and/or the activity of a ...
2022Akt Is S-Palmitoylated: A New Layer of Regulation for Akt
Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami
The protein kinase Akt/PKB participates in a great variety of processes, including translation, cell proliferation and survival, as well as malignant transformation and viral infection. In the last few years, novel Akt posttranslational modifications have ...
FRONTIERS MEDIA SA2021The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation
Liquid-liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein F ...
OXFORD UNIV PRESS2021Architecture of the centriole cartwheel‐containing region revealed by cryo‐electron tomography
Henning Paul-Julius Stahlberg, Paul Guichard, Virginie Hamel
Centrioles are evolutionarily conserved barrels of microtubule triplets that form the core of the centrosome and the base of the cilium. While the crucial role of the proximal region in centriole biogenesis has been well documented, its native architecture ...
2020Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells
Proper spindle positioning is crucial for spatial cell division control. Spindle positioning in human cells relies on a ternary complex comprising G alpha i1-3, LGN and NuMA, which anchors dynein at the cell cortex, thus enabling pulling forces to be exert ...
Springer2019