Concept
Thréonine
Publications associées (33)
Novel inhibitors of kallikrein proteases and uses thereof
Christian Heinis, Alessandro Zorzi, Patrick Andreas Gonschorek
The present invention relates to a cyclic inhibitor of a kallikrein protease comprising or consisting of (I) the peptide (X1 (X2)(X3)R(X4)(X5)(X6)(X7)(X8)(X9)(X10)(X11) (Formula (X)), wherein (X1) is present or absent and, is preferably present, and if pre ...
2021Radical-free hyperpolarized MRI using endogenously occurring pyruvate analogues and UV-induced nonpersistent radicals
Rolf Gruetter, Andrea Capozzi, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara, Alice Radaelli, Claudia Christina Zanella, Lionel Pierre Arn
It was recently demonstrated that nonpersistent radicals can be generated in frozen solutions of metabolites such as pyruvate by irradiation with UV light, enabling radical-free dissolution dynamic nuclear polarization. Although pyruvate is endogenous, the ...
WILEY2021Mild inborn errors of metabolism in commonly used inbred mouse strains
Johan Auwerx, Wei Zhang, Evan Graehl Williams
Inbred mouse strains are a cornerstone of translational research but paradoxically many strains carry mild inborn errors of metabolism. For example, alpha-aminoadipic acidemia and branched-chain ketoacid dehydrogenase deficiency are known in C57BL/6J mice. ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2019