Concept
Megestrol acetate
Concepts associés (22)
Acétate de médroxyprogestérone
L’acétate de médroxyprogestérone (en anglais Medroxyprogesterone acetate ou MPA), connu aussi sous le nom acétate de 17α-hydroxy-6α-méthylprogestérone, ou Depo-Provera est une forme synthétique de progestérone. Il est utilisé principalement comme contraceptif mais sert aussi pour le traitement de l'endométriose. Ses actions pharmacologiques sur le système endocrinien sont : L'inhibition des gonadotrophines hypophysaires : hormone folliculostimulante (FSH) et hormone lutéinisante (LH).
Cyproterone acetate
Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills. It is formulated and used both alone and in combination with an estrogen.
Hydroxyprogestérone caproate
Le caproate d'hydroxyprogestérone (OHPC), vendu sous les noms de marque Proluton et Makena entre autres, est un médicament progestatif utilisé pour prévenir l'accouchement prématuré chez les femmes enceintes ayant des antécédents de la maladie et pour traiter les troubles gynécologiques. Il a également été formulé en association avec des œstrogènes pour diverses indications (noms de marque Gravibinon et Primosiston) et sous forme de contraceptif injectable de longue durée (nom de marque Chinese Injectable No.
Hydroxyprogestérone
Modèle 3D ( JSmol ) CHEBI: 17252 Carte Info ECHA 5104 La 17α-hydroxyprogestérone (17α-OHP), également connue sous le nom de 17-OH progestérone (17-OHP), ou hydroxyprogestérone (OHP), est une hormone stéroïde progestative proche chimiquement de la progestérone. C'est également une structure intermédiaire dans la biosynthèse de nombreux autres stéroïdes biologiques, parmi eux, les androgènes, les œstrogènes, les glucocorticoïdes et les minéralocorticoïdes, ainsi que certains neuromédiateurs stéroïdiens.
Chlormadinone acetate
Chlormadinone acetate (CMA), sold under the brand names Belara, Gynorelle, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, in the treatment of gynecological disorders, and in the treatment of androgen-dependent conditions like enlarged prostate and prostate cancer in men and acne and hirsutism in women.
Progestogen ester
A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen). The prototypical progestogen is progesterone, an endogenous sex hormone. Esterification is frequently employed to improve the pharmacokinetics of steroids, including oral bioavailability, lipophilicity, and elimination half-life. In addition, with intramuscular injection, steroid esters are often absorbed more slowly into the body, allowing for less frequent administration. Many (though not all) steroid esters function as prodrugs.
Nomegestrol acetate
Nomegestrol acetate (NOMAC), sold under the brand names Lutenyl and Zoely among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. NOMAC is taken by mouth. A birth control implant for placement under the skin was also developed but ultimately was not marketed. Side effects of NOMAC include menstrual irregularities, headaches, nausea, breast tenderness, and others.
Steroidal antiandrogen
A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production. SAAs lower concentrations of testosterone through simulation of the negative feedback inhibition of the hypothalamus. SAAs are used in the treatment of androgen-dependent conditions in men and women, and are also used in veterinary medicine for the same purpose.
Nandrolone decanoate
Nandrolone decanoate, sold under the brand name ROLON among others, is an androgen and anabolic steroid (AAS) medication which is used primarily in the treatment of anemias and wasting syndromes, as well as osteoporosis in menopausal women. It is given by injection into muscle or fat once every one to four weeks. Side effects of nandrolone decanoate may include symptoms of masculinization like acne, increased hair growth, voice changes, and decreased sexual desire due to its ability to suppress endogenous testosterone synthesis while not being a sufficient androgen itself.
Combined injectable birth control
Combined injectable contraceptives (CICs) are a form of hormonal birth control for women. They consist of monthly injections of combined formulations containing an estrogen and a progestin to prevent pregnancy. CICs are different from progestogen-only injectable contraceptives (POICs), such as depot medroxyprogesterone acetate (DMPA; brand names Depo-Provera, Depo-SubQ Provera 104) and norethisterone enantate (NETE; brand name Noristerat), which are not combined with an estrogen and are given once every two to three months instead of once a month.