Publications associées à Cycle de Krebs

Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity

Florian Maria Wurm, Martin Jordan, Mathieu Benjamin Stettler, Francesca Zagari

Lactate production is monitored in industrial processes as a crucial metabolite for cultured mammalian cells. Typically lactate is strongly produced during the exponential growth phase, while its net consumption is frequently observed when cells enter into ...

Elsevier2013

Silver release from silver nanoparticles in natural waters

Rizlan Bernier-Latmani, Jan Dobias

Silver nanoparticles (AgNPs) are used increasingly in consumer products for their antimicrobial properties. This increased use raises ecological concern because of the release of AgNPs into the environment. Once released, zero-valent silver may be oxidized ...

American Chemical Society2013

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Rolf Gruetter, Mor-Miri Mishkovsky, João Miguel das Neves Duarte, Tian Cheng, Arnaud Comment, Josefina Adriana Maria Bastiaansen

BACKGROUND: Acetate metabolism in skeletal muscle is regulated by acetylCoA synthetase (ACS). The main function of ACS is to provide cells with acetylCoA, a key molecule for numerous metabolic pathways including fatty acid and cholesterol synthesis and the ...

Elsevier Science Bv2013

In vivo detection of brain Krebs cycle intermediate by hyperpolarized magnetic resonance

Rolf Gruetter, Mor-Miri Mishkovsky, Arnaud Comment

The Krebs (or tricarboxylic acid (TCA)) cycle has a central role in the regulation of brain energy regulation and metabolism, yet brain TCA cycle intermediates have never been directly detected in vivo. This study reports the first direct in vivo observati ...

Nature Publishing Group2012

Real-Time Noninvasive Imaging of Fatty Acid Uptake in Vivo

Gennady Nikitin

Detection and quantification of fatty acid fluxes in animal model systems following physiological, pathological, or pharmacological challenges is key to our understanding of complex metabolic networks as these macronutrients also activate transcription fac ...

American Chemical Society2012

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

Stewart Cole, Florence Pojer, Claudia Sala, Ruben Hartkoorn, Joao Pedro De Almeida Neres, Swapna Uplekar, Raju Mukherjee, Sophie Magnet

Tuberculosis, a global threat to public health, is becoming untreatable due to widespread drug resistance to frontline drugs such as the InhA-inhibitor isoniazid. Historically, by inhibiting highly vulnerable targets, natural products have been an importan ...

Wiley Open Access2012

Characterization of cerebral glucose dynamics in vivo with a four-state conformational model of transport at the blood-brain barrier

Rolf Gruetter, João Miguel das Neves Duarte

Determination of brain glucose transport kinetics in vivo at steady-state typically does not allow distinguishing apparent maximum transport rate (Tmax) from cerebral consumption rate. Using a four-state conformational model of glucose transport, we show t ...

Wiley-Blackwell2012

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Johan Auwerx, Richardus Houtkooper, Dongryeol Ryu

Resveratrol is a natural compound that affects energy metabolism and mitochondrial function and serves as a calorie restriction mimetic, at least in animal models of obesity. Here, we treated 11 healthy, obese men with placebo and 150 mg/day resveratrol (r ...

2011

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Cycle de Krebs

Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity

Silver release from silver nanoparticles in natural waters

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

In vivo detection of brain Krebs cycle intermediate by hyperpolarized magnetic resonance

Real-Time Noninvasive Imaging of Fatty Acid Uptake in Vivo

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

Characterization of cerebral glucose dynamics in vivo with a four-state conformational model of transport at the blood-brain barrier

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission

Preparation of 5-Membered Rings via Radical Addition-Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Graph Chatbot

Chattez avec Graph Search

Silver release from silver nanoparticles in natural waters

Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

In vivo detection of brain Krebs cycle intermediate by hyperpolarized magnetic resonance

Real-Time Noninvasive Imaging of Fatty Acid Uptake in Vivo

In vivo enzymatic activity of acetylCoA synthetase in skeletal muscle revealed by (13)C turnover from hyperpolarized [1-(13)C]acetate to [1-(13)C]acetylcarnitine

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Preparation of 5-Membered Rings via Radical Addition-Translocation-Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites

Characterization of cerebral glucose dynamics in vivo with a four-state conformational model of transport at the blood-brain barrier

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission