Concept

Cellule ganglionnaire

Publications associées (168)

See-through ophthalmoscope for retinal imaging

With the miniaturization of scanning mirrors and the emergence of wearable health monitoring, an intriguing step is to investigate the potential of a laser scanning ophthalmoscope (LSO) for retinal imaging with wearable glasses. In addition to providing mo ...

Spie-Soc Photo-Optical Instrumentation Engineers2017

Overcoming the resolution limit in retinal imaging using the scattering properties of the sclera

Demetri Psaltis, Christophe Moser, Timothé Laforest, Dino Carpentras

In-vivo imaging of the eye's fundus is widely used to study eye's health. State of the art Adaptive Optics devices can resolve features up to a lateral resolution of 1.5 um. This resolution is still above what is needed to observe subcellular structures su ...

Spie-Int Soc Optical Engineering2016

JNK Inhibition Reduced Retinal Ganglion Cell Death after Ischemia/Reperfusion In Vivo and after Hypoxia In Vitro

Tatiana Favez

Mitogen-activated protein kinases (MAPKs) are key regulators that have been linked to cell survival and death. Among the main classes of MAPKs, c-jun N-terminal kinase (JNK) has been shown to mediate cell stress responses associated with apoptosis. In Vitr ...

Springer Int Publishing Ag2016

Retina Color-Opponency Based Pursuit Implemented Through Spiking Neural Networks in the Neurorobotics Platform

Marc-Oliver Gewaltig, Egidio Falotico, Lorenzo Vannucci, Paul Levi, Georg Hinkel, Stefan Ulbrich, Alessandro Ambrosano, Ugo Albanese, Murat Kirtay

The 'red-green' pathway of the retina is classically recognized as one of the retinal mechanisms allowing humans to gather color information from light, by combining information from L-cones and M-cones in an opponent way. The precise retinal circuitry tha ...

Springer Int Publishing Ag2016

Mutations in the polyglutamylase geneTTLL5, expressed in photoreceptor cells and spermatozoa, are associated with cone-rod degeneration and reduced male fertility

Hereditary retinal degenerations encompass a group of genetic diseases characterized by extreme clinical variability. Following next-generation sequencing and autozygome-based screening of patients presenting with a peculiar, recessive form of cone-dominat ...

Oxford University Press2016

Characterization of a Polymer-Based, Fully Organic Prosthesis for Implantation into the Subretinal Space of the Rat

Diego Ghezzi

Replacement strategies arise as promising approaches in case of inherited retinal dystrophies leading to blindness. A fully organic retinal prosthesis made of conjugated polymers layered onto a silk fibroin substrate is engineered. First, the biophysical a ...

Wiley-VCH Verlag2016

Retinal prostheses: progress toward the next generation implants

Diego Ghezzi

In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aimin ...

Frontiers Research Foundation2015

Light-Evoked Modulation of Neuronal Activity with Conjugated Polymers

Diego Ghezzi, Mattia Nova

Organic bioelectronics aims at the intimate integration between organic materials and biological tissues in order to obtain a targeted functional outcome. In the last decades, conductive polymers have been successfully employed to interface excitable cells ...

2015

Elucidating the role of Hmx1 during mouse development

Linda Bapst

This thesis focuses on the study of H6 homeobox 1 (HMX1) gene, a homeobox-containing transcription factor involved in sensory organ and eye development and responsible for the oculo-auricular syndrome of Schorderet-Munier-Franceschetti. The purpose of my s ...

EPFL2015

Tgfbi/Bigh3 silencing activates ERK in mouse retina

BIGH3 is a secreted protein, part of the extracellular matrix where it interacts with collagen and integrins on the cell surface. BIGH3 can play opposing roles in cancer, acting as either tumor suppressor or promoter, and its mutations lead to different fo ...

Academic Press Ltd- Elsevier Science Ltd2015

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