Concept
Leucémie aiguë lymphoblastique
Publications associées (71)
Novel quantitative bioengineered tools to track human bone marrow niche cellular constituents in health and disease
Acute leukemia has a high mortality rate of approximately 50%, and current methods are not effective in predicting disease progression and relapse. To improve our understanding of hematopoiesis and develop new markers for predicting disease relapse in dead ...
EPFL2023Resistance mechanism to Notch inhibition and combination therapy in human T cell acute lymphoblastic leukemia
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy caused by acquisition of genetic alterations during T-cell development. The 5-year overall survival of pediatric T-ALL patients has improved considerably over the past 30 ...
EPFL2023Longitudinal evaluation of the mechanisms supporting post-stroke motor recovery using TMS-EEG coupling
Andéol Geoffroy Cadic-Melchior
Stroke is the main source of long-lasting disability, affecting dominantly motor functions. The extent and course of recovery are highly heterogeneous between patients, with a minority of patients fully recovering from their initial impairments, leaving 85 ...
EPFL2023Evaluation of tire tread particle toxicity to fish using rainbow trout cell lines
Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset, Gabrielle Léger
Tire and road wear particles (TRWP) resulting from tire abrasion while driving raise concerns due to their potential contribution to aquatic toxicity. Our study aimed to assess cryogenically milled tire tread (CMTT) particle toxicity, used as a proxy for T ...
2023