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Performance of any model-based control scheme depends on the quality of model. When these schemes deliver poor loop performance due to model-plant mismatch (MPM), a detection of the same needs to be in place. A recently introduced plant model ratio (PMR) n ...
The desire to operate chemical processes in a safe and economically optimal way has motivated the development of so-called real-time optimization (RTO) methods [1]. For continuous processes, these methods aim to compute safe and optimal steady-state set ...
This presentation discusses real-time optimization (RTO) strategies for improving process performance in the presence of uncertainty in the form of plant-model mismatch, drifts and disturbances. RTO typically uses a plant model to compute optimal inputs. I ...
Dynamic optimization can be used to determine optimal input profiles for dynamic processes. Due to plant-model mismatch and disturbances, the optimal inputs determined through model-based optimization will, in general, not be optimal for the plant. Modifie ...
Aurora kinases compose a family of conserved Ser/Thr protein kinases playing essential roles in eukaryotic cell division. To date, Aurora homologues remain uncharacterized in the protozoan phylum Apicomplexa. In malaria parasites, the characterization of A ...
This presentation discusses real-time optimization (RTO) strategies for improving process performance in the presence of uncertainty in the form of plant-model mismatch, drifts and disturbances. RTO typically uses a plant model to compute optimal inputs. I ...
Integral observers are useful tools for estimating the plant states in the presence of non-vanishing disturbances resulting from plant-model mismatch and exogenous disturbances. It is well known that these observers can eliminate bias in all states, given ...
Optimization is important in science and engineering as a way of finding ”optimal” situations, designs or operating conditions. Optimization is typically performed on the basis of a mathematical model of the process under investigation. In practice, optimi ...
The ability of a model-based real-time optimization scheme to converge to the plant optimum relies on the ability of the underlying process model to predict the plant's necessary conditions of optimality (NCO). These include the values and gradients of the ...
The process industries are characterized by a large number of continuously operating plants, for which optimal operation is of economic importance. However, optimal operation is particularly difficult to achieve when the process model used in the optimizat ...
