Concept

Hypertrophie bénigne de la prostate

Publications associées (51)

Separable Effects for Causal Inference in the Presence of Competing Events

In time-to-event settings, the presence of competing events complicates the definition of causal effects. Here we propose the new separable effects to study the causal effect of a treatment on an event of interest. The separable direct effect is the treatm ...

2020

Estimation of separable direct and indirect effects in continuous time

Mats Julius Stensrud

Many research questions involve time-to-event outcomes that can be prevented from occurring due to competing events. In these settings, we must be careful about the causal interpretation of classical statistical estimands. In particular, estimands on the h ...

2020

Memristive Biosensors based on Full-size Antibodies and Antibody Fragments

Giovanni De Micheli, Sandro Carrara, Ioulia Tzouvadaki, Sébastien Naus

For the first time memristive biosensors developed by the incorporation of scAbs (single-chain antibody fragments) enabling label-free detection of free Prostate Specific Antigen (fPSA) for early-stage detection of prostate cancer (PC) are reported. In add ...

2019

The miR-96 and RAR gamma signaling axis governs androgen signaling and prostate cancer progression

Gerard Llimos Aubach

Expression levels of retinoic acid receptor gamma (NR1B3/RARG, encodes RAR gamma) are commonly reduced in prostate cancer (PCa). Therefore, we sought to establish the cellular and gene regulatory consequences of reduced RAR gamma expression, and determine ...

Springer2019

An extended regulatory landscape drives Tbx18 activity in a variety of prostate-associated cell lineages

Christopher Chase Bolt, Soumya Negi

The evolutionarily conserved transcription factor, Tbx18, is expressed in a dynamic pattern throughout embryonic and early postnatal life and plays crucial roles in the development of multiple organ systems. Previous studies have indicated that this dynami ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Urine-Contactless Device to Empty Bladders: an Ex-Vivo Proof-of-Concept Study in Porcine Bladders

Yves Perriard, Yoan René Cyrille Civet, Francesco Clavica

Current treatments for underactive bladder (UAB) have negative side effects, such as urinary tract infections, mainly because devices used for bladder emptying are in direct contact with urine (e.g. permanent or intermittent catheterisation). Moreover, mos ...

Wiley2019

Portable Memristive Biosensing System as Effective Point-of-Care Device for Cancer Diagnostics

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Ioulia Tzouvadaki, Abuduwaili Tuoheti

Memristive biosensors have been proved as excellent candidates for ultrasensitive biosensing. In this work, a novel portable bio-detection system based on memristive biosensors is designed, developed and tested for providing a significantly fast, automatic ...

IEEE2018

Novel Concept Enabling an Old Idea: A Flexible Electrode Array to Treat Neurogenic Erectile Dysfunction

Mikaël Nils Sturny

Introduction: Many studies have shown that electrostimulation of the cavernosal nerve can induce and maintain penile erection. Based on these discoveries, neurostimulation to activate the erectile response has been considered a potential solution to treat ...

ELSEVIER SCI LTD2018

Bimodal CD40/Fas-Dependent Crosstalk between iNKT Cells and Tumor-Associated Macrophages Impairs Prostate Cancer Progression

Michele De Palma, Ferdinando Pucci, Alessandra Recchia

Heterotypic cellular and molecular interactions in the tumor microenvironment (TME) control cancer progression. Here, we show that CD1d-restricted invariant natural killer (iNKT) cells control prostate cancer (PCa) progression by sculpting the TME. In a mo ...

Elsevier B.V.2018

Folic acid on iron oxide nanoparticles: platform with high potential for simultaneous targeting, MRI detection and hyperthermia treatment of lymph node metastases of prostate cancer

Heinrich Hofmann, Josefina Adriana Maria Bastiaansen, Marijana Mionic Ebersold, Débora Bonvin

The overexpression of the folate receptor in most cancers has been widely exploited to specifically deliver folic acid (FA) coupled nanomedicines to tumors. However, complex coupling chemistry is often used to bind FA to the nanoparticles. Furthermore, ver ...

Royal Society of Chemistry2017

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